The deposition of immunoglobulins and complement components in osteoarthritic cartilage

T. D V Cooke, E. L. Bennett, O. Ohno

Research output: Contribution to journalArticle

Abstract

In a prospective study of 117 patients having reconstructive surgery for osteoarthritis, biopsies of hyaline articular cartilage and meniscal fibrocartilage were taken which exhibited immunofluorescence in their articular surfaces, for at least two immuno-globulins (Ig) and β1c. These could represent immune complexes. The cases were classified into three Groups according to clinical, radiological and laboratory features, (1) non-arthritic - 27 (3% positive); (2) secondary degenerative - 32 (16% positive); (3) idiopathic osteoarthritic - 89 (51% positive). The incidence of positive findings in Group III was significant at p

Original languageEnglish (US)
Pages (from-to)211-217
Number of pages7
JournalInternational Orthopaedics
Volume4
Issue number3
DOIs
StatePublished - Nov 1980
Externally publishedYes

Fingerprint

Reconstructive Surgical Procedures
Fibrocartilage
Hyaline Cartilage
Globulins
Articular Cartilage
Antigen-Antibody Complex
Osteoarthritis
Cartilage
Fluorescent Antibody Technique
Immunoglobulins
Joints
Prospective Studies
Biopsy
Incidence

Keywords

  • Cartilage
  • Immunoglobulins deposition
  • Osteoarthritis

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

The deposition of immunoglobulins and complement components in osteoarthritic cartilage. / Cooke, T. D V; Bennett, E. L.; Ohno, O.

In: International Orthopaedics, Vol. 4, No. 3, 11.1980, p. 211-217.

Research output: Contribution to journalArticle

Cooke, T. D V ; Bennett, E. L. ; Ohno, O. / The deposition of immunoglobulins and complement components in osteoarthritic cartilage. In: International Orthopaedics. 1980 ; Vol. 4, No. 3. pp. 211-217.
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