The Dark Side of Estrogen Stops Translation to Induce Apoptosis

Research output: Contribution to journalShort surveypeer-review

Abstract

The role of hormones in triggering cell death has been controversial. In this issue of Molecular Cell, Li et al. (2019) have defined a molecular pathway where an unexpected estrogen receptor, phosphodiesterase 3A, allows its partner Schlafen-12 to inhibit survival pathways, ultimately leading to apoptosis.

Original languageEnglish (US)
Pages (from-to)1087-1089
Number of pages3
JournalMolecular cell
Volume75
Issue number6
DOIs
StatePublished - Sep 19 2019

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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