The D7 family of salivary proteins in blood sucking diptera

J. G. Valenzuela, R. Charlab, E. C. Gonzalez, I. K.F. De Miranda-Santos, O. Marinotti, I. M.B. Francischetti, J. M.C. Ribeiro

Research output: Contribution to journalArticlepeer-review


The D7 subfamily of salivary proteins is widespread in blood sucking Diptera and belongs to the superfamily of pheromone/odourant binding proteins. Although D7 proteins are among the most abundant salivary proteins in adult female mosquitoes and sand flies, their role in blood feeding remains elusive. In the present work we report the sequence of seventeen novel D7 proteins, and propose an evolutionary scenario for the appearance of the several forms of this protein, based on a total of twenty-one sequences from Culex quinquefasciatus, Aedes aegypti, Anopheles gambiae, An. arabiensis, An. stephensi, An. darlingi mosquitoes and Lutzomyia longipalpis and Phlebotomus papatasi sand flies.

Original languageEnglish (US)
Pages (from-to)149-155
Number of pages7
JournalInsect molecular biology
Issue number2
StatePublished - 2002
Externally publishedYes


  • Haemostasis
  • Mosquito
  • Saliva
  • Salivary glands
  • Sandfly

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Insect Science


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