The conversion of l-valine to glucose and glycogen in the rat

William S. Fones; T. Phillip Waalkes; Julius White

doi:10.1016/0003-9861(51)90241-X

The conversion of l-valine to glucose and glycogen in the rat

William S. Fones, T. Phillip Waalkes, Julius White

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Abstract

l-Valine labeled in the methyl groups has been fed to fasting as well as to phlorizinized rats. Glycogen and glucose have been isolated and degraded. The glucose and glycogen were found to be uniformly labeled and a possible explanation for this observation is given. It was shown that, depending on the level of l-valine administration, up to 38% of the isotope was expired as carbon dioxide. At higher levels of administration a considerable percentage (about 15% in 8 hr.) of the isotope was excreted in the urine.

Original language	English (US)
Pages (from-to)	89-95
Number of pages	7
Journal	Archives of Biochemistry and Biophysics
Volume	32
Issue number	1
DOIs	https://doi.org/10.1016/0003-9861(51)90241-X
State	Published - Jun 1951
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology

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title = "The conversion of l-valine to glucose and glycogen in the rat",

abstract = "l-Valine labeled in the methyl groups has been fed to fasting as well as to phlorizinized rats. Glycogen and glucose have been isolated and degraded. The glucose and glycogen were found to be uniformly labeled and a possible explanation for this observation is given. It was shown that, depending on the level of l-valine administration, up to 38% of the isotope was expired as carbon dioxide. At higher levels of administration a considerable percentage (about 15% in 8 hr.) of the isotope was excreted in the urine.",

author = "Fones, {William S.} and Waalkes, {T. Phillip} and Julius White",

note = "Funding Information: Cancer Institute, National Institutes of Health, Public Health Service, Federal Security Agency, Bethesda, Maryland Received January 29, 1951",

year = "1951",

month = jun,

doi = "10.1016/0003-9861(51)90241-X",

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AU - Fones, William S.

AU - Waalkes, T. Phillip

AU - White, Julius

N1 - Funding Information: Cancer Institute, National Institutes of Health, Public Health Service, Federal Security Agency, Bethesda, Maryland Received January 29, 1951

PY - 1951/6

Y1 - 1951/6

N2 - l-Valine labeled in the methyl groups has been fed to fasting as well as to phlorizinized rats. Glycogen and glucose have been isolated and degraded. The glucose and glycogen were found to be uniformly labeled and a possible explanation for this observation is given. It was shown that, depending on the level of l-valine administration, up to 38% of the isotope was expired as carbon dioxide. At higher levels of administration a considerable percentage (about 15% in 8 hr.) of the isotope was excreted in the urine.

AB - l-Valine labeled in the methyl groups has been fed to fasting as well as to phlorizinized rats. Glycogen and glucose have been isolated and degraded. The glucose and glycogen were found to be uniformly labeled and a possible explanation for this observation is given. It was shown that, depending on the level of l-valine administration, up to 38% of the isotope was expired as carbon dioxide. At higher levels of administration a considerable percentage (about 15% in 8 hr.) of the isotope was excreted in the urine.

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The conversion of l-valine to glucose and glycogen in the rat

Abstract

ASJC Scopus subject areas

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