The control of gastric emptying

Research output: Contribution to journalArticle

Abstract

The control of gastric emptying has been restudied. Methods used are described. It was found that in the alert unanesthetized monkey saline is emptied from the stomach at a rate that is volume-dependent; an exponential curve results since higher volumes provoke more rapid emptying and lower volumes slower emptying. For glucose test meals emptying is quite linear; also emptying is slower and progressively slower with progressive increases in glucose concentration. There is, however, an early rapid phase of gastric emptying that converts to a slower, more linear pattern. Calories rather than osmoles appear to control emptying. Glucose in the pyloris has an inhibitory effect in gastric emptying. A theory of control is discussed. The control of gastric emptying also relates to the control of feeding.

Original languageEnglish (US)
Pages (from-to)221-231
Number of pages11
JournalJournal of the Autonomic Nervous System
Volume9
Issue number1
DOIs
StatePublished - Oct 1983

Keywords

  • calorie intake
  • control theory
  • gastric emptying
  • inhibitory feedback
  • pyloric control
  • steady state

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'The control of gastric emptying'. Together they form a unique fingerprint.

  • Cite this