The control of gastric emptying

Research output: Contribution to journalArticlepeer-review

Abstract

The control of gastric emptying has been restudied. Methods used are described. It was found that in the alert unanesthetized monkey saline is emptied from the stomach at a rate that is volume-dependent; an exponential curve results since higher volumes provoke more rapid emptying and lower volumes slower emptying. For glucose test meals emptying is quite linear; also emptying is slower and progressively slower with progressive increases in glucose concentration. There is, however, an early rapid phase of gastric emptying that converts to a slower, more linear pattern. Calories rather than osmoles appear to control emptying. Glucose in the pyloris has an inhibitory effect in gastric emptying. A theory of control is discussed. The control of gastric emptying also relates to the control of feeding.

Original languageEnglish (US)
Pages (from-to)221-231
Number of pages11
JournalJournal of the Autonomic Nervous System
Volume9
Issue number1
DOIs
StatePublished - Oct 1983

Keywords

  • calorie intake
  • control theory
  • gastric emptying
  • inhibitory feedback
  • pyloric control
  • steady state

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology
  • Clinical Neurology

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