TY - JOUR
T1 - The contribution of urinary cations to the blood pressure differences associated with migration
AU - Klag, Michael J.
AU - He, Jiang
AU - Coresh, Josef
AU - Whelton, Paul K.
AU - Chen, Jun Yun
AU - Mo, Jing Ping
AU - Qian, Ming Chu
AU - Mo, Pei Sheng
AU - He, Guan Qing
N1 - Funding Information:
This study was supported by the Ministry of Public Health, People's Republic of China, and was partially supported by Outpatient General Research Center grant 5M01RR00722 from the US National Institutes of Health (NIH). Computational assistance was received from NIH grant RR00035.
PY - 1995/8/1
Y1 - 1995/8/1
N2 - People living in unacculturated societies have a low average blood pressure and little rise in blood pressure with age. In a community-based survey in southwestern China, the authors assessed the contribution of urinary cation excretion to differences in blood pressure between an unacculturated group (Yi farmers) and migrants to an urban environment, as well as urban controls from a different ethnic group (Han). In March 1989, blood pressure and overnight urinary electrolyte levels were measured on 3 consecutive days in 313 Yi farmers, 265 Yi migrants, and 253 urban Han residents, all male. Of the urinary electrolytes, a higher sodium: potassium ratio best explained the higher blood pressure in the migrants. Yi farmers had lower systolic (106.7 mmHg vs. 114.8 mmHg, respectively) and diastolic (66.2 mmHg vs. 71.3 mmHg, respectively) blood pressures than Yi migrants. However, even after adjustment for age, body mass index, alcohol intake, and urinary sodium, potassium, calcium, and magnesium excretion, Yi farmers continued to have lower average blood pressures than Yi migrants. In pooled analyses of all three groups, urinary sodium and calcium were positively related and urinary potassium and magnesium were inversely related to blood pressure. Migration is associated with a higher blood pressure that is only partially explained by higher levels of adiposity and alcohol and sodium intake and lower levels of potassium and magnesium intake.
AB - People living in unacculturated societies have a low average blood pressure and little rise in blood pressure with age. In a community-based survey in southwestern China, the authors assessed the contribution of urinary cation excretion to differences in blood pressure between an unacculturated group (Yi farmers) and migrants to an urban environment, as well as urban controls from a different ethnic group (Han). In March 1989, blood pressure and overnight urinary electrolyte levels were measured on 3 consecutive days in 313 Yi farmers, 265 Yi migrants, and 253 urban Han residents, all male. Of the urinary electrolytes, a higher sodium: potassium ratio best explained the higher blood pressure in the migrants. Yi farmers had lower systolic (106.7 mmHg vs. 114.8 mmHg, respectively) and diastolic (66.2 mmHg vs. 71.3 mmHg, respectively) blood pressures than Yi migrants. However, even after adjustment for age, body mass index, alcohol intake, and urinary sodium, potassium, calcium, and magnesium excretion, Yi farmers continued to have lower average blood pressures than Yi migrants. In pooled analyses of all three groups, urinary sodium and calcium were positively related and urinary potassium and magnesium were inversely related to blood pressure. Migration is associated with a higher blood pressure that is only partially explained by higher levels of adiposity and alcohol and sodium intake and lower levels of potassium and magnesium intake.
KW - Blood pressure
KW - Electrolytes
KW - Hypertension
KW - Nutrition
KW - Transients and migrants
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U2 - 10.1093/oxfordjournals.aje.a117635
DO - 10.1093/oxfordjournals.aje.a117635
M3 - Article
C2 - 7631633
AN - SCOPUS:0029156435
SN - 0002-9262
VL - 142
SP - 295
EP - 303
JO - American journal of epidemiology
JF - American journal of epidemiology
IS - 3
ER -