The conjoint influence of home enriched environment and lead exposure on children's cognition and behaviour in a Mexican lead smelter community

Sue Moodie, Nicholas S Ialongo, Patricia López, Jorge Rosado, Gonzalo García-Vargas, Dolores Ronquillo, Katarzyna Kordas

Research output: Contribution to journalArticle

Abstract

A range of studies has been conducted on the detrimental effects of lead in mining and smelting communities. The neurocognitive and behavioural health effects of lead on children are well known. This research characterized the conjoint influence of lead exposure and home enriched environment on neurocognitive function and behaviour for first-grade children living in a Mexican lead smelter community.Structural equation models were used for this analysis with latent outcome variables, Cognition and Behaviour, constructed based on a battery of assessments administered to the first-grade children, their parents, and teachers. Structural equation modelling was used to describe complex relationships of exposure and health outcomes in a manner that permitted partition of both direct and indirect effects of the factors being measured.Home Environment (a latent variable constructed from information on mother's education and support of school work and extracurricular activities), and child blood lead concentration each had a main significant effect on cognition and behaviour. However, there were no statistically significant moderation relationships between lead and Home Environment on these latent outcomes. Home Environment had a significant indirect mediation effect between lead and both Cognition and Behaviour (p-value <0.001). The mediation model had a good fit with Root Mean Square Error of Approximation

Original languageEnglish (US)
Pages (from-to)33-41
Number of pages9
JournalNeuroToxicology
Volume34
Issue number1
DOIs
StatePublished - Jan 2013

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Child Behavior
Cognition
Health
Structural Models
Smelting
Mean square error
Lead
Blood
Education
Parents
Mothers
Research

Keywords

  • Behaviour
  • Child health
  • Cognition
  • Home environment
  • Lead
  • Mining community

ASJC Scopus subject areas

  • Neuroscience(all)
  • Toxicology

Cite this

The conjoint influence of home enriched environment and lead exposure on children's cognition and behaviour in a Mexican lead smelter community. / Moodie, Sue; Ialongo, Nicholas S; López, Patricia; Rosado, Jorge; García-Vargas, Gonzalo; Ronquillo, Dolores; Kordas, Katarzyna.

In: NeuroToxicology, Vol. 34, No. 1, 01.2013, p. 33-41.

Research output: Contribution to journalArticle

Moodie, Sue ; Ialongo, Nicholas S ; López, Patricia ; Rosado, Jorge ; García-Vargas, Gonzalo ; Ronquillo, Dolores ; Kordas, Katarzyna. / The conjoint influence of home enriched environment and lead exposure on children's cognition and behaviour in a Mexican lead smelter community. In: NeuroToxicology. 2013 ; Vol. 34, No. 1. pp. 33-41.
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