The complete nucleotide sequence of the Crossostoma lacustre mitochondrial genome: Conservation and variations among vertebrates

Chyng Shyan Tzeng, Cho Fat Hui, Shih Chieh Shen, P C Huang

Research output: Contribution to journalArticle

Abstract

The complete mitochondrial (mt) genome of Crossostoma lacustre, a freshwater loach from mountain stream of Taiwan, has been cloned and sequenced. This fish mt genome, consisting of 16558 base-pairs, encodes genes for 13 proteins, two rRNAs, and 22 tRNAs, in addition to a regulatory sequence for replication and transcription (D-loop), is similar to those of the other vertebrates in both the order and orientation of these genes. The protein-coding and ribosomal RNA genes are highly homologous both in size and composition, to their counterparts in mammals, birds, amphibians, and invertebrates, and using essentially the same set of codons, including both the initiation and termination signals, and the tRNAs. Differences do exist, however, in the lengths and sequences of the D-loop regions, and in space between genes, which account for the variations in total lengths of the genomes. Our observations provide evidence for the first time for the conservation of genetic information in the fish mitochondrial genome, especially among the vertebrates.

Original languageEnglish (US)
Pages (from-to)4853-4858
Number of pages6
JournalNucleic Acids Research
Volume20
Issue number18
StatePublished - Sep 25 1992

Fingerprint

Mitochondrial Genome
Nucleotides
Vertebrates
Conservation
Genome
Genes
Transfer RNA
Gene
Fishes
Fish
Cypriniformes
Gene Order
Amphibians
Invertebrates
Fresh Water
Protein
Taiwan
rRNA Genes
Codon
Base Pairing

ASJC Scopus subject areas

  • Genetics
  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Health, Toxicology and Mutagenesis
  • Toxicology
  • Genetics(clinical)

Cite this

The complete nucleotide sequence of the Crossostoma lacustre mitochondrial genome : Conservation and variations among vertebrates. / Tzeng, Chyng Shyan; Hui, Cho Fat; Shen, Shih Chieh; Huang, P C.

In: Nucleic Acids Research, Vol. 20, No. 18, 25.09.1992, p. 4853-4858.

Research output: Contribution to journalArticle

@article{73d3453b3dce4276951e125ae02ff8fd,
title = "The complete nucleotide sequence of the Crossostoma lacustre mitochondrial genome: Conservation and variations among vertebrates",
abstract = "The complete mitochondrial (mt) genome of Crossostoma lacustre, a freshwater loach from mountain stream of Taiwan, has been cloned and sequenced. This fish mt genome, consisting of 16558 base-pairs, encodes genes for 13 proteins, two rRNAs, and 22 tRNAs, in addition to a regulatory sequence for replication and transcription (D-loop), is similar to those of the other vertebrates in both the order and orientation of these genes. The protein-coding and ribosomal RNA genes are highly homologous both in size and composition, to their counterparts in mammals, birds, amphibians, and invertebrates, and using essentially the same set of codons, including both the initiation and termination signals, and the tRNAs. Differences do exist, however, in the lengths and sequences of the D-loop regions, and in space between genes, which account for the variations in total lengths of the genomes. Our observations provide evidence for the first time for the conservation of genetic information in the fish mitochondrial genome, especially among the vertebrates.",
author = "Tzeng, {Chyng Shyan} and Hui, {Cho Fat} and Shen, {Shih Chieh} and Huang, {P C}",
year = "1992",
month = "9",
day = "25",
language = "English (US)",
volume = "20",
pages = "4853--4858",
journal = "Nucleic Acids Research",
issn = "1362-4962",
publisher = "Oxford University Press",
number = "18",

}

TY - JOUR

T1 - The complete nucleotide sequence of the Crossostoma lacustre mitochondrial genome

T2 - Conservation and variations among vertebrates

AU - Tzeng, Chyng Shyan

AU - Hui, Cho Fat

AU - Shen, Shih Chieh

AU - Huang, P C

PY - 1992/9/25

Y1 - 1992/9/25

N2 - The complete mitochondrial (mt) genome of Crossostoma lacustre, a freshwater loach from mountain stream of Taiwan, has been cloned and sequenced. This fish mt genome, consisting of 16558 base-pairs, encodes genes for 13 proteins, two rRNAs, and 22 tRNAs, in addition to a regulatory sequence for replication and transcription (D-loop), is similar to those of the other vertebrates in both the order and orientation of these genes. The protein-coding and ribosomal RNA genes are highly homologous both in size and composition, to their counterparts in mammals, birds, amphibians, and invertebrates, and using essentially the same set of codons, including both the initiation and termination signals, and the tRNAs. Differences do exist, however, in the lengths and sequences of the D-loop regions, and in space between genes, which account for the variations in total lengths of the genomes. Our observations provide evidence for the first time for the conservation of genetic information in the fish mitochondrial genome, especially among the vertebrates.

AB - The complete mitochondrial (mt) genome of Crossostoma lacustre, a freshwater loach from mountain stream of Taiwan, has been cloned and sequenced. This fish mt genome, consisting of 16558 base-pairs, encodes genes for 13 proteins, two rRNAs, and 22 tRNAs, in addition to a regulatory sequence for replication and transcription (D-loop), is similar to those of the other vertebrates in both the order and orientation of these genes. The protein-coding and ribosomal RNA genes are highly homologous both in size and composition, to their counterparts in mammals, birds, amphibians, and invertebrates, and using essentially the same set of codons, including both the initiation and termination signals, and the tRNAs. Differences do exist, however, in the lengths and sequences of the D-loop regions, and in space between genes, which account for the variations in total lengths of the genomes. Our observations provide evidence for the first time for the conservation of genetic information in the fish mitochondrial genome, especially among the vertebrates.

UR - http://www.scopus.com/inward/record.url?scp=0026670894&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026670894&partnerID=8YFLogxK

M3 - Article

C2 - 1408800

AN - SCOPUS:0026670894

VL - 20

SP - 4853

EP - 4858

JO - Nucleic Acids Research

JF - Nucleic Acids Research

SN - 1362-4962

IS - 18

ER -