The Complement System in AMD

P. Charbel Issa; N. V. Chong; H. P.N. Scholl

doi:10.1007/978-3-642-22107-1_4

The Complement System in AMD

P. Charbel Issa, N. V. Chong, H. P.N. Scholl

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Age-related macular degeneration (AMD) is a complex disease with genetic, environmental, and demographic risk factors (see previous chapters). In recent years, there has been growing evidence that the inflammatory processes, including dysregulation of the complement system, play a major role in the pathogenesis of AMD. The discovery of genetic polymorphisms in genes coding for complement proteins that affect patients’ susceptibility to AMD propelled research in establishing the complement system as a key component in the pathogenesis of AMD [1].

Original language	English (US)
Title of host publication	Age-Related Macular Degeneration
Publisher	Springer Berlin Heidelberg
Pages	65-76
Number of pages	12
ISBN (Electronic)	9783642221071
ISBN (Print)	9783642221064
DOIs	https://doi.org/10.1007/978-3-642-22107-1_4
State	Published - Jan 1 2013

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-642-22107-1_4

Cite this

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abstract = "Age-related macular degeneration (AMD) is a complex disease with genetic, environmental, and demographic risk factors (see previous chapters). In recent years, there has been growing evidence that the inflammatory processes, including dysregulation of the complement system, play a major role in the pathogenesis of AMD. The discovery of genetic polymorphisms in genes coding for complement proteins that affect patients{\textquoteright} susceptibility to AMD propelled research in establishing the complement system as a key component in the pathogenesis of AMD [1].",

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AB - Age-related macular degeneration (AMD) is a complex disease with genetic, environmental, and demographic risk factors (see previous chapters). In recent years, there has been growing evidence that the inflammatory processes, including dysregulation of the complement system, play a major role in the pathogenesis of AMD. The discovery of genetic polymorphisms in genes coding for complement proteins that affect patients’ susceptibility to AMD propelled research in establishing the complement system as a key component in the pathogenesis of AMD [1].

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The Complement System in AMD

Abstract

ASJC Scopus subject areas

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