The Complement System in AMD

P. Charbel Issa, N. V. Chong, H. P N Scholl

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Age-related macular degeneration (AMD) is a complex disease with genetic, environmental, and demo­graphic risk factors (see previous chapters). In recent years, there has been growing evidence that the inflammatory processes, including dysregulation of the complement system, play a major role in the pathogenesis of AMD. The discovery of genetic polymorphisms in genes coding for complement proteins that affect patients’ susceptibility to AMD propelled research in establishing the complement system as a key component in the pathogenesis of AMD [1].

Original languageEnglish (US)
Title of host publicationAge-Related Macular Degeneration
PublisherSpringer Berlin Heidelberg
Pages65-76
Number of pages12
ISBN (Electronic)9783642221071
ISBN (Print)9783642221064
DOIs
StatePublished - Jan 1 2013

Fingerprint

Macular Degeneration
Inborn Genetic Diseases
Genetic Polymorphisms
Complement System Proteins
Demography
Research
Genes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Charbel Issa, P., Chong, N. V., & Scholl, H. P. N. (2013). The Complement System in AMD. In Age-Related Macular Degeneration (pp. 65-76). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-22107-1_4

The Complement System in AMD. / Charbel Issa, P.; Chong, N. V.; Scholl, H. P N.

Age-Related Macular Degeneration. Springer Berlin Heidelberg, 2013. p. 65-76.

Research output: Chapter in Book/Report/Conference proceedingChapter

Charbel Issa, P, Chong, NV & Scholl, HPN 2013, The Complement System in AMD. in Age-Related Macular Degeneration. Springer Berlin Heidelberg, pp. 65-76. https://doi.org/10.1007/978-3-642-22107-1_4
Charbel Issa P, Chong NV, Scholl HPN. The Complement System in AMD. In Age-Related Macular Degeneration. Springer Berlin Heidelberg. 2013. p. 65-76 https://doi.org/10.1007/978-3-642-22107-1_4
Charbel Issa, P. ; Chong, N. V. ; Scholl, H. P N. / The Complement System in AMD. Age-Related Macular Degeneration. Springer Berlin Heidelberg, 2013. pp. 65-76
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