The Comparative Clearance Rates of the Pleural and Peritoneal Cavities

Constantine Mavroudis, Mark A. Malangoni, Sara L. Katzmark, Richard Montgomery, C. Randolph Schrodt, Hiram C. Polk

Research output: Contribution to journalArticle

Abstract

We compared the rates of bacterial clearance from the pleural and peritoneal cavities of rats after contamination with 1 × 106 live Escherichia coli. Pleural clearance was enhanced beginning at 30 minutes after injection and extended to at least six hours. At 24 hours, the clearance was similar for both the pleural and peritoneal groups. Blood and organ bacterial cultures were similar between these two groups. White blood cell populations were similar at rest, but there was a greater increase in the leukocyte population in the pleural cavity six hours after E coli stimulation. We postulate that the increased clearance of E coli from the pleural cavity may be due to differences in lymphatic absorption, recruitment of leukocytes, or fibrin trapping of bacteria.

Original languageEnglish (US)
Pages (from-to)157-161
Number of pages5
JournalArchives of Surgery
Volume123
Issue number2
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

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Pleural Cavity
Peritoneal Cavity
Leukocytes
Escherichia coli
Organ Culture Techniques
Fibrin
Population
Bacteria
Injections

ASJC Scopus subject areas

  • Surgery

Cite this

Mavroudis, C., Malangoni, M. A., Katzmark, S. L., Montgomery, R., Schrodt, C. R., & Polk, H. C. (1988). The Comparative Clearance Rates of the Pleural and Peritoneal Cavities. Archives of Surgery, 123(2), 157-161. https://doi.org/10.1001/archsurg.1988.01400260037003

The Comparative Clearance Rates of the Pleural and Peritoneal Cavities. / Mavroudis, Constantine; Malangoni, Mark A.; Katzmark, Sara L.; Montgomery, Richard; Schrodt, C. Randolph; Polk, Hiram C.

In: Archives of Surgery, Vol. 123, No. 2, 01.01.1988, p. 157-161.

Research output: Contribution to journalArticle

Mavroudis, C, Malangoni, MA, Katzmark, SL, Montgomery, R, Schrodt, CR & Polk, HC 1988, 'The Comparative Clearance Rates of the Pleural and Peritoneal Cavities', Archives of Surgery, vol. 123, no. 2, pp. 157-161. https://doi.org/10.1001/archsurg.1988.01400260037003
Mavroudis, Constantine ; Malangoni, Mark A. ; Katzmark, Sara L. ; Montgomery, Richard ; Schrodt, C. Randolph ; Polk, Hiram C. / The Comparative Clearance Rates of the Pleural and Peritoneal Cavities. In: Archives of Surgery. 1988 ; Vol. 123, No. 2. pp. 157-161.
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