The Churg Strauss Syndrome

Joseph A. Eustace, Tibor Nadasdy, Michael Choi

Research output: Contribution to journalArticle

Abstract

The Churg Strauss Syndrome is an eosinophil-associated small vessel vasculitis. Although its pathogenesis may be distinctive and the association with severe late-onset asthma typical, the clinical features during the vasculitic phase widely overlap with those of the other forms of necrotizing vasculitis, and no single clinical or histologic feature is pathognomic of the condition. Renal involvement is common, although usually mild, and even when severe it tends to respond well to treatment. The prognosis for both patient and renal survival with adequate treatment is in general good. The optimal treatment strategy, however, is uncertain, and may differ from that for the other vasculitides. In particular, in contrast to Wegener's granulomatosis, the need for routine cyclophosphamide treatment is unconfirmed and requires further study.

Original languageEnglish (US)
Pages (from-to)2048-2055
Number of pages8
JournalJournal of the American Society of Nephrology
Volume10
Issue number9
StatePublished - Sep 1 1999

ASJC Scopus subject areas

  • Nephrology

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    Eustace, J. A., Nadasdy, T., & Choi, M. (1999). The Churg Strauss Syndrome. Journal of the American Society of Nephrology, 10(9), 2048-2055.