The cheetah is depauperate in genetic variation

Stephen J. O'Brien, David E. Wildt, David Goldman, Carl R. Merril, Mitchell Bush

Research output: Contribution to journalArticle

Abstract

A sample of 55 South African cheetahs (Acinonyx jubatus jubatus) from two geographically isolated populations in South Africa were found to be genetically monomorphic at each of 47 allozyme (allelic isozyme) loci. Two-dimensional gel electrophoresis of 155 abundant soluble proteins from cheetah fibroblasts also revealed a low frequency of polymorphism (average heterozygosity, 0.013). Both estimates are dramatically lower than levels of variation reported in other cats and mammals in general. The extreme monomorphism may be a consequence of a demographic contraction of the cheetah (a population bottleneck) in association with a reduced rate of increase in the recent natural history of this endangered species.

Original languageEnglish (US)
Pages (from-to)459-462
Number of pages4
JournalScience
Volume221
Issue number4609
StatePublished - 1983
Externally publishedYes

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Acinonyx jubatus
genetic variation
two-dimensional gel electrophoresis
natural history
endangered species
fibroblasts
isozymes
heterozygosity
demographic statistics
South Africa
genetic polymorphism
mammals
cats
loci
proteins
sampling

ASJC Scopus subject areas

  • General

Cite this

O'Brien, S. J., Wildt, D. E., Goldman, D., Merril, C. R., & Bush, M. (1983). The cheetah is depauperate in genetic variation. Science, 221(4609), 459-462.

The cheetah is depauperate in genetic variation. / O'Brien, Stephen J.; Wildt, David E.; Goldman, David; Merril, Carl R.; Bush, Mitchell.

In: Science, Vol. 221, No. 4609, 1983, p. 459-462.

Research output: Contribution to journalArticle

O'Brien, SJ, Wildt, DE, Goldman, D, Merril, CR & Bush, M 1983, 'The cheetah is depauperate in genetic variation', Science, vol. 221, no. 4609, pp. 459-462.
O'Brien SJ, Wildt DE, Goldman D, Merril CR, Bush M. The cheetah is depauperate in genetic variation. Science. 1983;221(4609):459-462.
O'Brien, Stephen J. ; Wildt, David E. ; Goldman, David ; Merril, Carl R. ; Bush, Mitchell. / The cheetah is depauperate in genetic variation. In: Science. 1983 ; Vol. 221, No. 4609. pp. 459-462.
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