The cerebroplacental Doppler ratio revisited

Ahmet Baschat, U. Gembruch

Research output: Contribution to journalArticle

Abstract

Objective: To evaluate the distribution of Doppler pulsatility index (PI) measurements of the umbilical and middle cerebral arteries in singleton fetuses of women with normal uterine artery blood flow and to construct reference ranges for the cerebroplacental PI Doppler ratio. Methods: The PI was determined in the mid-portion of the umbilical artery and the mid- or distal segment of the middle cerebral artery in 306 normal singleton fetuses. The cerebroplacental Doppler ratio (CPR) was determined from paired measurements. After determination of the best fit, reference ranges were constructed for each parameter against gestational age (GA). Results: The PI for the umbilical artery had a linear relationship with GA (umbilical artery PI = -0.0246 × GA + 1.7791, r2 = 0.4025, P <0.001). The middle cerebral artery PI and the CPR both showed a quadratic relationship with GA (middle cerebral artery PI = -0.0058 × GA2 + 0.3335 × GA -2.7317, r2 = 0.2365, P <0.01), (CPR = -0.0059 × GA2 + 0.383 × GA 4.0636, r2 = 0.2788, P <0.001). Conclusion: The CPR is not constant throughout gestation. Reference ranges constructed by a standardized Doppler technique may he of benefit in the monitoring of high-risk pregnancies.

Original languageEnglish (US)
Pages (from-to)124-127
Number of pages4
JournalUltrasound in Obstetrics and Gynecology
Volume21
Issue number2
DOIs
StatePublished - Feb 1 2003
Externally publishedYes

Fingerprint

arteries
Gestational Age
Middle Cerebral Artery
Umbilical Arteries
Reference Values
fetuses
Fetus
Umbilicus
High-Risk Pregnancy
Uterine Artery
pregnancy
blood flow
Pregnancy

Keywords

  • Cerebral blood flow
  • Cerebroplacental ratio
  • Doppler ultrasound
  • Umbilical blood flow

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Reproductive Medicine
  • Acoustics and Ultrasonics

Cite this

The cerebroplacental Doppler ratio revisited. / Baschat, Ahmet; Gembruch, U.

In: Ultrasound in Obstetrics and Gynecology, Vol. 21, No. 2, 01.02.2003, p. 124-127.

Research output: Contribution to journalArticle

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