The CEPH Consortium Linkage Map of Human Chromosome 13

Anne M. Bowcock, Steven C. Gerken, Robert I. Barnes, Rita Shiang, Ethylin Wang Jabs, Andrew C. Warren, Stylianos Antonarakis, Andries E. Retief, Gilles Vergnaud, Mark Leppert, Jean Marc Lalouel, Raymond L. White, L. Luca Cavalli-Sforza

Research output: Contribution to journalArticle

Abstract

The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158,203, and 178 cM respectively. The largest interval is 24 cM and is between D13Z1 (alphaRI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM.

Original languageEnglish (US)
Pages (from-to)486-496
Number of pages11
JournalGenomics
Volume16
Issue number2
DOIs
Publication statusPublished - May 1993

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ASJC Scopus subject areas

  • Genetics

Cite this

Bowcock, A. M., Gerken, S. C., Barnes, R. I., Shiang, R., Jabs, E. W., Warren, A. C., ... Cavalli-Sforza, L. L. (1993). The CEPH Consortium Linkage Map of Human Chromosome 13. Genomics, 16(2), 486-496. https://doi.org/10.1006/geno.1993.1215