The CEPH consortium linkage map of human chromosome 13

Anne M. Bowcock; Steven C. Gerken; Robert I. Barnes; Rita Shiang; Ethylin Wang Jabs; Andrew C. Warren; Stylianos Antonarakis; Andries E. Retief; Gilles Vergnaud; Mark Leppert; Jean Marc Lalouel; Raymond L. White; L. Luca Cavalli-Sforza

doi:10.1006/geno.1993.1215

The CEPH consortium linkage map of human chromosome 13

Anne M. Bowcock, Steven C. Gerken, Robert I. Barnes, Rita Shiang, Ethylin Wang Jabs, Andrew C. Warren, Stylianos Antonarakis, Andries E. Retief, Gilles Vergnaud, Mark Leppert, Jean Marc Lalouel, Raymond L. White, L. Luca Cavalli-Sforza

School of Medicine

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158,203, and 178 cM respectively. The largest interval is 24 cM and is between D13Z1 (alphaRI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM.

Original language	English (US)
Pages (from-to)	486-496
Number of pages	11
Journal	Genomics
Volume	16
Issue number	2
DOIs	https://doi.org/10.1006/geno.1993.1215
State	Published - May 1993

ASJC Scopus subject areas

Genetics

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10.1006/geno.1993.1215

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title = "The CEPH consortium linkage map of human chromosome 13",

abstract = "The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158,203, and 178 cM respectively. The largest interval is 24 cM and is between D13Z1 (alphaRI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM.",

author = "Bowcock, {Anne M.} and Gerken, {Steven C.} and Barnes, {Robert I.} and Rita Shiang and Jabs, {Ethylin Wang} and Warren, {Andrew C.} and Stylianos Antonarakis and Retief, {Andries E.} and Gilles Vergnaud and Mark Leppert and Lalouel, {Jean Marc} and White, {Raymond L.} and Cavalli-Sforza, {L. Luca}",

year = "1993",

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T1 - The CEPH consortium linkage map of human chromosome 13

AU - Bowcock, Anne M.

AU - Gerken, Steven C.

AU - Barnes, Robert I.

AU - Shiang, Rita

AU - Jabs, Ethylin Wang

AU - Warren, Andrew C.

AU - Antonarakis, Stylianos

AU - Retief, Andries E.

AU - Vergnaud, Gilles

AU - Leppert, Mark

AU - Lalouel, Jean Marc

AU - White, Raymond L.

AU - Cavalli-Sforza, L. Luca

PY - 1993/5

Y1 - 1993/5

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AB - The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158,203, and 178 cM respectively. The largest interval is 24 cM and is between D13Z1 (alphaRI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM.

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JO - Genomics

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The CEPH consortium linkage map of human chromosome 13

Abstract

ASJC Scopus subject areas

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