The cardiovascular toll of stress

Research output: Contribution to journalReview article

Abstract

Psychological stress elicits measurable changes in sympathetic-parasympathetic balance and the tone of the hypothalamic-pituitary-adrenal axis, which might negatively affect the cardiovascular system both acutely-by precipitating myocardial infarction, left-ventricular dysfunction, or dysrhythmia; and chronically-by accelerating the atherosclerotic process. We provide an overview of the association between stress and cardiovascular morbidity, discuss the mechanisms for this association, and address possible therapeutic implications.

Original languageEnglish (US)
Pages (from-to)1089-1100
Number of pages12
JournalLancet
Volume370
Issue number9592
DOIs
StatePublished - Sep 22 2007

ASJC Scopus subject areas

  • Medicine(all)

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