The cardiac atlas project: Rationale, design and procedures

Carissa G. Fonseca, Michael Backhaus, Jae Do Chung, Wenchao Tao, Pau Medrano-Gracia, Brett R. Cowan, Peter J. Hunter, J. Paul Finn, Kalyanam Shivkumar, Joao A.C. Lima, David A. Bluemke, Alan H. Kadish, Daniel C. Lee, Alistair A. Young

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The Cardiac Atlas Project (CAP) is a NIH sponsored international collaboration to establish a web-accessible structural and functional atlas of the normal and pathological heart as a resource for the clinical, research and educational communities. An initial goal of the atlas is to facilitate statistical analysis of regional heart shape and wall motion characteristics, and characterization of remodeling, between and within population groups. The two main early contributing studies are the Multi Ethnic Study of Atherosclerosis (MESA) and the Defibrillators to Reduce Risk by Magnetic Resonance Imaging Evaluation (DETERMINE) clinical trial. De-identified image and text data from 2864 asymptomatic volunteers from MESA, and 470 myocardial infarction cases from DETERMINE, are currently available in the CAP database. DICOM images were de-identified using HIPAA compliant software based on tools provided by the Center for Computational Biology at UCLA. Only those cases with informed consent and IRB approval compatible with the CAP were included. Researchers requesting permission to access CAP data can apply through the CAP website (www.cardiacatlas.org). All proposals for data access must be approved by the data contributors, and applicants must sign a data transfer agreement with each study from which data is requested. Software to visualize cardiac images and create 3D mathematical models, developed in the CAP, is available open-source from the website.

Original languageEnglish (US)
Title of host publicationStatistical Atlases and Computational Models of the Heart - First Int. Workshop, STACOM 2010 and Cardiac Electrophysiological Simulation Challenge, CESC 2010 - Held in Conj. with MICCAI 2010, Proc.
Pages36-45
Number of pages10
DOIs
StatePublished - 2010
Event1st International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2010 and Cardiac Electrophysiological Simulation Challenge, CESC 2010 - Held in Conjunction with MICCAI 2010 - Beijing, China
Duration: Sep 20 2010Sep 20 2010

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume6364 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other1st International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2010 and Cardiac Electrophysiological Simulation Challenge, CESC 2010 - Held in Conjunction with MICCAI 2010
Country/TerritoryChina
CityBeijing
Period9/20/109/20/10

Keywords

  • Cardiac
  • Computational Atlas
  • Database
  • Mapping

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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