The biology/disease-driven human proteome project (B/D-HPP): Enabling protein research for the life sciences community

Ruedi Aebersold, Gary D. Bader, Aled M. Edwards, Jennifer E. Van Eyk, Martin Kussmann, Jun Qin, Gilbert S. Omenn

Research output: Contribution to journalReview article

Abstract

The biology and disease oriented branch of the Human Proteome Project (B/D-HPP) was established by the Human Proteome Organization (HUPO) with the main goal of supporting the broad application of state-of theart measurements of proteins and proteomes by life scientists studying the molecular mechanisms of biological processes and human disease. This will be accomplished through the generation of research and informational resources that will support the routine and definitive measurement of the process or disease relevant proteins. The B/D-HPP is highly complementary to the C-HPP and will provide datasets and biological characterization useful to the C-HPP teams. In this manuscript we describe the goals, the plans, and the current status of the of the B/D-HPP.

Original languageEnglish (US)
Pages (from-to)23-27
Number of pages5
JournalJournal of proteome research
Volume12
Issue number1
DOIs
StatePublished - Jan 4 2013

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Keywords

  • Affinity reagents
  • Biological processes
  • Human disease
  • Human proteome project
  • Mass spectrometry
  • Network biology
  • Proteomics

ASJC Scopus subject areas

  • Biochemistry
  • Chemistry(all)

Cite this

Aebersold, R., Bader, G. D., Edwards, A. M., Van Eyk, J. E., Kussmann, M., Qin, J., & Omenn, G. S. (2013). The biology/disease-driven human proteome project (B/D-HPP): Enabling protein research for the life sciences community. Journal of proteome research, 12(1), 23-27. https://doi.org/10.1021/pr301151m