The Banff 2007 working classification of skin-containing composite tissue allograft pathology

L. C. Cendales, J. Kanitakis, S. Schneeberger, C. Burns, P. Ruiz, L. Landin, M. Remmelink, C. W. Hewitt, T. Landgren, B. Lyons, C. B. Drachenberg, K. Solez, A. D. Kirk, D. E. Kleiner, Lorraine C Racusen

Research output: Contribution to journalArticle

Abstract

Composite tissue allotransplantation (CTA) is a recently introduced option for limb replacement and reconstruction of tissue defects. As with other allografts, CTA can undergo immune-mediated rejection; therefore standardized criteria are required for characterizing and reporting severity and types of rejection. This article documents the conclusions of a symposium on CTA rejection held at the Ninth Banff Conference on Allograft Pathology in La-Coruňa, Spain, on 26 June 2007, and proposes a working classification, the Banff CTA-07, for the categorization of CTA rejection. This classification was derived from a consensus discussion session attended by the first authors of three published classification systems, pathologists and researchers from international centers where clinical CTA has been performed. It was open to all attendees to the Banff conference. To the extent possible, the format followed the established National Institutes of Health (NIH) guidelines on Consensus Development Programs. By consensus, the defining features to diagnose acute skin rejection include inflammatory cell infiltration with involvement of epidermis and/or adnexal structures, epithelial apoptosis, dyskeratosis and necrosis. Five grades of severity of rejection are defined. This classification refines proposed schemas, represents international consensus on this topic, and establishes a working collective classification system for CTA reporting of rejection in skin-containing CTAs.

Original languageEnglish (US)
Pages (from-to)1396-1400
Number of pages5
JournalAmerican Journal of Transplantation
Volume8
Issue number7
DOIs
StatePublished - Jul 2008

Fingerprint

Composite Tissue Allografts
Vascularized Composite Allotransplantation
Pathology
Skin
Consensus
Allografts
National Institutes of Health (U.S.)
Rejection (Psychology)
Epidermis
Spain
Necrosis
Extremities
Research Personnel
Guidelines
Apoptosis

Keywords

  • Anitbody-mediated rejection
  • Banff
  • Banff schema
  • Chronic rejection
  • Composite tissue allograft
  • Humoral rejection
  • Rejection
  • Skin allograft
  • Transplant

ASJC Scopus subject areas

  • Immunology

Cite this

Cendales, L. C., Kanitakis, J., Schneeberger, S., Burns, C., Ruiz, P., Landin, L., ... Racusen, L. C. (2008). The Banff 2007 working classification of skin-containing composite tissue allograft pathology. American Journal of Transplantation, 8(7), 1396-1400. https://doi.org/10.1111/j.1600-6143.2008.02243.x

The Banff 2007 working classification of skin-containing composite tissue allograft pathology. / Cendales, L. C.; Kanitakis, J.; Schneeberger, S.; Burns, C.; Ruiz, P.; Landin, L.; Remmelink, M.; Hewitt, C. W.; Landgren, T.; Lyons, B.; Drachenberg, C. B.; Solez, K.; Kirk, A. D.; Kleiner, D. E.; Racusen, Lorraine C.

In: American Journal of Transplantation, Vol. 8, No. 7, 07.2008, p. 1396-1400.

Research output: Contribution to journalArticle

Cendales, LC, Kanitakis, J, Schneeberger, S, Burns, C, Ruiz, P, Landin, L, Remmelink, M, Hewitt, CW, Landgren, T, Lyons, B, Drachenberg, CB, Solez, K, Kirk, AD, Kleiner, DE & Racusen, LC 2008, 'The Banff 2007 working classification of skin-containing composite tissue allograft pathology', American Journal of Transplantation, vol. 8, no. 7, pp. 1396-1400. https://doi.org/10.1111/j.1600-6143.2008.02243.x
Cendales, L. C. ; Kanitakis, J. ; Schneeberger, S. ; Burns, C. ; Ruiz, P. ; Landin, L. ; Remmelink, M. ; Hewitt, C. W. ; Landgren, T. ; Lyons, B. ; Drachenberg, C. B. ; Solez, K. ; Kirk, A. D. ; Kleiner, D. E. ; Racusen, Lorraine C. / The Banff 2007 working classification of skin-containing composite tissue allograft pathology. In: American Journal of Transplantation. 2008 ; Vol. 8, No. 7. pp. 1396-1400.
@article{6789ba0cf01c4b4d821f1f1431379ca2,
title = "The Banff 2007 working classification of skin-containing composite tissue allograft pathology",
abstract = "Composite tissue allotransplantation (CTA) is a recently introduced option for limb replacement and reconstruction of tissue defects. As with other allografts, CTA can undergo immune-mediated rejection; therefore standardized criteria are required for characterizing and reporting severity and types of rejection. This article documents the conclusions of a symposium on CTA rejection held at the Ninth Banff Conference on Allograft Pathology in La-Coruňa, Spain, on 26 June 2007, and proposes a working classification, the Banff CTA-07, for the categorization of CTA rejection. This classification was derived from a consensus discussion session attended by the first authors of three published classification systems, pathologists and researchers from international centers where clinical CTA has been performed. It was open to all attendees to the Banff conference. To the extent possible, the format followed the established National Institutes of Health (NIH) guidelines on Consensus Development Programs. By consensus, the defining features to diagnose acute skin rejection include inflammatory cell infiltration with involvement of epidermis and/or adnexal structures, epithelial apoptosis, dyskeratosis and necrosis. Five grades of severity of rejection are defined. This classification refines proposed schemas, represents international consensus on this topic, and establishes a working collective classification system for CTA reporting of rejection in skin-containing CTAs.",
keywords = "Anitbody-mediated rejection, Banff, Banff schema, Chronic rejection, Composite tissue allograft, Humoral rejection, Rejection, Skin allograft, Transplant",
author = "Cendales, {L. C.} and J. Kanitakis and S. Schneeberger and C. Burns and P. Ruiz and L. Landin and M. Remmelink and Hewitt, {C. W.} and T. Landgren and B. Lyons and Drachenberg, {C. B.} and K. Solez and Kirk, {A. D.} and Kleiner, {D. E.} and Racusen, {Lorraine C}",
year = "2008",
month = "7",
doi = "10.1111/j.1600-6143.2008.02243.x",
language = "English (US)",
volume = "8",
pages = "1396--1400",
journal = "American Journal of Transplantation",
issn = "1600-6135",
publisher = "Wiley-Blackwell",
number = "7",

}

TY - JOUR

T1 - The Banff 2007 working classification of skin-containing composite tissue allograft pathology

AU - Cendales, L. C.

AU - Kanitakis, J.

AU - Schneeberger, S.

AU - Burns, C.

AU - Ruiz, P.

AU - Landin, L.

AU - Remmelink, M.

AU - Hewitt, C. W.

AU - Landgren, T.

AU - Lyons, B.

AU - Drachenberg, C. B.

AU - Solez, K.

AU - Kirk, A. D.

AU - Kleiner, D. E.

AU - Racusen, Lorraine C

PY - 2008/7

Y1 - 2008/7

N2 - Composite tissue allotransplantation (CTA) is a recently introduced option for limb replacement and reconstruction of tissue defects. As with other allografts, CTA can undergo immune-mediated rejection; therefore standardized criteria are required for characterizing and reporting severity and types of rejection. This article documents the conclusions of a symposium on CTA rejection held at the Ninth Banff Conference on Allograft Pathology in La-Coruňa, Spain, on 26 June 2007, and proposes a working classification, the Banff CTA-07, for the categorization of CTA rejection. This classification was derived from a consensus discussion session attended by the first authors of three published classification systems, pathologists and researchers from international centers where clinical CTA has been performed. It was open to all attendees to the Banff conference. To the extent possible, the format followed the established National Institutes of Health (NIH) guidelines on Consensus Development Programs. By consensus, the defining features to diagnose acute skin rejection include inflammatory cell infiltration with involvement of epidermis and/or adnexal structures, epithelial apoptosis, dyskeratosis and necrosis. Five grades of severity of rejection are defined. This classification refines proposed schemas, represents international consensus on this topic, and establishes a working collective classification system for CTA reporting of rejection in skin-containing CTAs.

AB - Composite tissue allotransplantation (CTA) is a recently introduced option for limb replacement and reconstruction of tissue defects. As with other allografts, CTA can undergo immune-mediated rejection; therefore standardized criteria are required for characterizing and reporting severity and types of rejection. This article documents the conclusions of a symposium on CTA rejection held at the Ninth Banff Conference on Allograft Pathology in La-Coruňa, Spain, on 26 June 2007, and proposes a working classification, the Banff CTA-07, for the categorization of CTA rejection. This classification was derived from a consensus discussion session attended by the first authors of three published classification systems, pathologists and researchers from international centers where clinical CTA has been performed. It was open to all attendees to the Banff conference. To the extent possible, the format followed the established National Institutes of Health (NIH) guidelines on Consensus Development Programs. By consensus, the defining features to diagnose acute skin rejection include inflammatory cell infiltration with involvement of epidermis and/or adnexal structures, epithelial apoptosis, dyskeratosis and necrosis. Five grades of severity of rejection are defined. This classification refines proposed schemas, represents international consensus on this topic, and establishes a working collective classification system for CTA reporting of rejection in skin-containing CTAs.

KW - Anitbody-mediated rejection

KW - Banff

KW - Banff schema

KW - Chronic rejection

KW - Composite tissue allograft

KW - Humoral rejection

KW - Rejection

KW - Skin allograft

KW - Transplant

UR - http://www.scopus.com/inward/record.url?scp=47249148415&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=47249148415&partnerID=8YFLogxK

U2 - 10.1111/j.1600-6143.2008.02243.x

DO - 10.1111/j.1600-6143.2008.02243.x

M3 - Article

VL - 8

SP - 1396

EP - 1400

JO - American Journal of Transplantation

JF - American Journal of Transplantation

SN - 1600-6135

IS - 7

ER -