The Balance Between Excitation And Inhibition And Functional Sensory Processing In The Somatosensory Cortex

Zhi Zhang, Qian Quan Sun

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The balance between excitation and inhibition (E/I balance) is tightly regulated in adult cortices to maintain proper nervous system function. Disturbed E/I balance is associated with numerous neuropsychological disorders, such as autism, epilepsy and schizophrenia. The present review will discuss aspects of Hebbian and homeostatic mechanisms regulating excitatory and inhibitory balance related to sensory processing in somatosensory cortex of rodents. Additionally, changes in the E/I balance during sensory manipulation will be discussed.

Original languageEnglish (US)
Title of host publicationInternational Review of Neurobiology
PublisherAcademic Press Inc.
Pages305-333
Number of pages29
DOIs
StatePublished - 2011

Publication series

NameInternational Review of Neurobiology
Volume97
ISSN (Print)0074-7742
ISSN (Electronic)0074-7742

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Keywords

  • Critical period
  • E/I balance
  • GABAergic interneuron
  • Neocortex
  • NMDA receptors
  • Postnatal development

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience

Cite this

Zhang, Z., & Sun, Q. Q. (2011). The Balance Between Excitation And Inhibition And Functional Sensory Processing In The Somatosensory Cortex. In International Review of Neurobiology (pp. 305-333). (International Review of Neurobiology; Vol. 97). Academic Press Inc.. https://doi.org/10.1016/B978-0-12-385198-7.00012-6