The bacteriology of aspiration pneumonia

John Bartlett, Sherwood L. Gorbach, Sydney M. Finegold

Research output: Contribution to journalArticle

Abstract

A prospective study of 54 cases of pulmonary infection following aspiration was performed. Specimens utilized for bacteriologic study were either transtracheal aspirates, empyema fluid or blood. Appropriate anaerobic bacteriologie methods were employed. Anaerobic bacteria were recovered in 50 patients (93 per cent) and were the only pathogens in 25 (46 per cent). The predominant species were Bacteroides melanino-genicus, Fusobacterium nucleatum and anaerobic or microaerophilic gram-positive cocci. Bacteroides fragilis, which is resistant to many commonly used antibiotics, was recovered in nine patients (17 per cent). Aerobic and facultative bacteria were present in 29 patients (54 per cent), but anaerobes were present concurrently in all but 4. Enteric gram-negative bacilli and pseudomonads were particularly common in patients whose disease developed in the hospital. Eleven patients with mixed aerobic and anaerobic infections were treated successfully with antibiotics which were active only against the anaerobic isolates, thereby further implicating the pathogenic role of these microorganisms. The results indicate that anaerobes play a key role in most cases of infection following aspiration.

Original languageEnglish (US)
Pages (from-to)202-207
Number of pages6
JournalAmerican Journal of Medicine
Volume56
Issue number2
DOIs
StatePublished - 1974
Externally publishedYes

Fingerprint

Aspiration Pneumonia
Bacteriology
Infection
Fusobacterium nucleatum
Anti-Bacterial Agents
Gram-Positive Cocci
Bacteroides fragilis
Aerobic Bacteria
Empyema
Bacteroides
Anaerobic Bacteria
Bacillus
Prospective Studies
Lung

ASJC Scopus subject areas

  • Nursing(all)

Cite this

The bacteriology of aspiration pneumonia. / Bartlett, John; Gorbach, Sherwood L.; Finegold, Sydney M.

In: American Journal of Medicine, Vol. 56, No. 2, 1974, p. 202-207.

Research output: Contribution to journalArticle

Bartlett, John ; Gorbach, Sherwood L. ; Finegold, Sydney M. / The bacteriology of aspiration pneumonia. In: American Journal of Medicine. 1974 ; Vol. 56, No. 2. pp. 202-207.
@article{a0dfd15e60b24317b603ea1b3e88de1c,
title = "The bacteriology of aspiration pneumonia",
abstract = "A prospective study of 54 cases of pulmonary infection following aspiration was performed. Specimens utilized for bacteriologic study were either transtracheal aspirates, empyema fluid or blood. Appropriate anaerobic bacteriologie methods were employed. Anaerobic bacteria were recovered in 50 patients (93 per cent) and were the only pathogens in 25 (46 per cent). The predominant species were Bacteroides melanino-genicus, Fusobacterium nucleatum and anaerobic or microaerophilic gram-positive cocci. Bacteroides fragilis, which is resistant to many commonly used antibiotics, was recovered in nine patients (17 per cent). Aerobic and facultative bacteria were present in 29 patients (54 per cent), but anaerobes were present concurrently in all but 4. Enteric gram-negative bacilli and pseudomonads were particularly common in patients whose disease developed in the hospital. Eleven patients with mixed aerobic and anaerobic infections were treated successfully with antibiotics which were active only against the anaerobic isolates, thereby further implicating the pathogenic role of these microorganisms. The results indicate that anaerobes play a key role in most cases of infection following aspiration.",
author = "John Bartlett and Gorbach, {Sherwood L.} and Finegold, {Sydney M.}",
year = "1974",
doi = "10.1016/0002-9343(74)90598-1",
language = "English (US)",
volume = "56",
pages = "202--207",
journal = "American Journal of Medicine",
issn = "0002-9343",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - The bacteriology of aspiration pneumonia

AU - Bartlett, John

AU - Gorbach, Sherwood L.

AU - Finegold, Sydney M.

PY - 1974

Y1 - 1974

N2 - A prospective study of 54 cases of pulmonary infection following aspiration was performed. Specimens utilized for bacteriologic study were either transtracheal aspirates, empyema fluid or blood. Appropriate anaerobic bacteriologie methods were employed. Anaerobic bacteria were recovered in 50 patients (93 per cent) and were the only pathogens in 25 (46 per cent). The predominant species were Bacteroides melanino-genicus, Fusobacterium nucleatum and anaerobic or microaerophilic gram-positive cocci. Bacteroides fragilis, which is resistant to many commonly used antibiotics, was recovered in nine patients (17 per cent). Aerobic and facultative bacteria were present in 29 patients (54 per cent), but anaerobes were present concurrently in all but 4. Enteric gram-negative bacilli and pseudomonads were particularly common in patients whose disease developed in the hospital. Eleven patients with mixed aerobic and anaerobic infections were treated successfully with antibiotics which were active only against the anaerobic isolates, thereby further implicating the pathogenic role of these microorganisms. The results indicate that anaerobes play a key role in most cases of infection following aspiration.

AB - A prospective study of 54 cases of pulmonary infection following aspiration was performed. Specimens utilized for bacteriologic study were either transtracheal aspirates, empyema fluid or blood. Appropriate anaerobic bacteriologie methods were employed. Anaerobic bacteria were recovered in 50 patients (93 per cent) and were the only pathogens in 25 (46 per cent). The predominant species were Bacteroides melanino-genicus, Fusobacterium nucleatum and anaerobic or microaerophilic gram-positive cocci. Bacteroides fragilis, which is resistant to many commonly used antibiotics, was recovered in nine patients (17 per cent). Aerobic and facultative bacteria were present in 29 patients (54 per cent), but anaerobes were present concurrently in all but 4. Enteric gram-negative bacilli and pseudomonads were particularly common in patients whose disease developed in the hospital. Eleven patients with mixed aerobic and anaerobic infections were treated successfully with antibiotics which were active only against the anaerobic isolates, thereby further implicating the pathogenic role of these microorganisms. The results indicate that anaerobes play a key role in most cases of infection following aspiration.

UR - http://www.scopus.com/inward/record.url?scp=0015979788&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015979788&partnerID=8YFLogxK

U2 - 10.1016/0002-9343(74)90598-1

DO - 10.1016/0002-9343(74)90598-1

M3 - Article

C2 - 4812076

AN - SCOPUS:0015979788

VL - 56

SP - 202

EP - 207

JO - American Journal of Medicine

JF - American Journal of Medicine

SN - 0002-9343

IS - 2

ER -