The axonal transport of βIII-tubulin is altered in both branches of sensory axons after injury of the rat sciatic nerve

Paul N. Hoffman, Richard F. Luduena

Research output: Contribution to journalArticle

Abstract

We have analyzed the axonal transport of βIII-tubulin in the central (dorsal root) and peripheral (sciatic nerve) branches of sensory axons after injury of the sciatic nerve. Our finding that the relative amount of βIII-tubulin transported in slow component b (SCb) is increased in both axonal branches does not support the generally accepted hypothesis that the transport of cytoskeletal proteins is altered in the peripheral, but not the central branch after injury of the sciatic nerve.

Original languageEnglish (US)
Pages (from-to)182-184
Number of pages3
JournalBrain research
Volume708
Issue number1-2
DOIs
StatePublished - Feb 5 1996

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Keywords

  • Axon regeneration
  • Axonal transport
  • Axotomy
  • Cytoskeleton
  • Dorsal root
  • Sciatic nerve
  • Sensory neuron
  • β-Tubulin

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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