The association of the cortisol awakening response with experimental pain ratings

L. A. Fabian, L. McGuire, G. G. Page, B. R. Goodin, R. R. Edwards, J. Haythornthwaite

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Cortisol is a key stress hormone that is implicated in a variety of physiological responses. Attenuated Cortisol Awakening Response (CAR) is associated with many negative health outcomes, but little research has investigated CAR and pain. The current study examines the association of CAR with experimental acute-pain ratings in healthy men and women. Attenuated CAR was related to greater pain intensity and unpleasantness ratings. Future research should examine this association across various pain populations.

Original languageEnglish (US)
Pages (from-to)1247-1251
Number of pages5
Issue number8
StatePublished - Sep 2009


  • Acute pain
  • Area under the curve
  • Cold pressor task
  • Cortisol awakening response
  • Cortisol diurnal rhythm

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Endocrine and Autonomic Systems
  • Psychiatry and Mental health
  • Biological Psychiatry


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