The association of current hormonal contraceptive use with type-specific HPV detection

Khalil G. Ghanem, S. Deblina Datta, Elizabeth R. Unger, Michael Hagensee, Judith C. Shlay, Peter Kerndt, Katherine Hsu, Laura A. Koutsky

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Increased duration of hormonal contraceptive (HC) use may be positively associated with the risk of invasive cervical cancer. Methods: This is a secondary analysis from the HPV Sentinel Surveillance Study. The authors examined the association between type-specific human papillomavirus (HPV) detection and current HC use among 7718 women attending 26 sexually transmitted disease, family planning and primary care clinics in the USA. Results: There was an association between HC use and HPV-16 detection (adjusted prevalence rate ratio 1.34 (95% CI 1.05 to 1.71) for oral contraceptive users and 1.41 (1.01 to 2.04) for depot-medroxyprogesterone acetate users); there was no association between HC use and detection of other HPV types or any HPV overall. Conclusions: Longitudinal studies are needed to better define this type-specific association and its clinical significance.

Original languageEnglish (US)
Pages (from-to)385-388
Number of pages4
JournalSexually transmitted infections
Volume87
Issue number5
DOIs
StatePublished - Aug 2011

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

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