The Association between Preoperative Frailty and Postoperative Delirium after Cardiac Surgery

Charles H. Brown, Laura Max, Andrew Laflam, Lou Kirk, Alden Gross, Rakesh Arora, Karin Neufeld, Charles W. Hogue, Jeremy Walston, Aliaksei Pustavoitau

Research output: Contribution to journalArticlepeer-review

Abstract

Delirium is common after cardiac surgery, and preoperative identification of high-risk patients could guide prevention strategies. We prospectively measured frailty in 55 patients before cardiac surgery and assessed postoperative delirium using a validated chart review. The prevalence of frailty was 30.9%. Frail patients had a higher incidence of delirium (47.1%) compared with nonfrail patients (2.6%; P < 0.001). In multivariable models, the relative risk of delirium was ≥2.1-fold greater in frail compared with nonfrail patients (relative risk, 18.3; 95% confidence interval, 2.1-161.8; P = 0.009). Frailty may identify patients who would benefit from delirium-prevention strategies because of increased baseline risk for delirium.

Original languageEnglish (US)
Pages (from-to)430-435
Number of pages6
JournalAnesthesia and analgesia
Volume123
Issue number2
DOIs
StatePublished - Aug 1 2016

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Fingerprint Dive into the research topics of 'The Association between Preoperative Frailty and Postoperative Delirium after Cardiac Surgery'. Together they form a unique fingerprint.

Cite this