The Association Between Preoperative Frailty and Postoperative Delirium After Cardiac Surgery

Charles Brown, Laura Max, Andrew LaFlam, Lou Kirk, Alden L Gross, Rakesh Arora, Karin Jane Neufeld, Charles W. Hogue, Jeremy D Walston, Aliaksei Pustavoitau

Research output: Contribution to journalArticle

Abstract

Delirium is common after cardiac surgery, and preoperative identification of high-risk patients could guide prevention strategies. We prospectively measured frailty in 55 patients before cardiac surgery and assessed postoperative delirium using a validated chart review. The prevalence of frailty was 30.9%. Frail patients had a higher incidence of delirium (47.1%) compared with nonfrail patients (2.6%; P <0.001). In multivariable models, the relative risk of delirium was ≥2.1-fold greater in frail compared with nonfrail patients (relative risk, 18.3; 95% confidence interval, 2.1–161.8; P = 0.009). Frailty may identify patients who would benefit from delirium-prevention strategies because of increased baseline risk for delirium.

Original languageEnglish (US)
JournalAnesthesia and Analgesia
DOIs
StateAccepted/In press - Apr 19 2016

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Delirium
Thoracic Surgery
Confidence Intervals
Incidence

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

The Association Between Preoperative Frailty and Postoperative Delirium After Cardiac Surgery. / Brown, Charles; Max, Laura; LaFlam, Andrew; Kirk, Lou; Gross, Alden L; Arora, Rakesh; Neufeld, Karin Jane; Hogue, Charles W.; Walston, Jeremy D; Pustavoitau, Aliaksei.

In: Anesthesia and Analgesia, 19.04.2016.

Research output: Contribution to journalArticle

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