Abstract
Delirium is common after cardiac surgery, and preoperative identification of high-risk patients could guide prevention strategies. We prospectively measured frailty in 55 patients before cardiac surgery and assessed postoperative delirium using a validated chart review. The prevalence of frailty was 30.9%. Frail patients had a higher incidence of delirium (47.1%) compared with nonfrail patients (2.6%; P <0.001). In multivariable models, the relative risk of delirium was ≥2.1-fold greater in frail compared with nonfrail patients (relative risk, 18.3; 95% confidence interval, 2.1–161.8; P = 0.009). Frailty may identify patients who would benefit from delirium-prevention strategies because of increased baseline risk for delirium.
| Original language | English (US) |
|---|---|
| Journal | Anesthesia and Analgesia |
| DOIs | |
| State | Accepted/In press - Apr 19 2016 |
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ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
The Association Between Preoperative Frailty and Postoperative Delirium After Cardiac Surgery. / Brown, Charles; Max, Laura; LaFlam, Andrew; Kirk, Lou; Gross, Alden L; Arora, Rakesh; Neufeld, Karin Jane; Hogue, Charles W.; Walston, Jeremy D; Pustavoitau, Aliaksei.
In: Anesthesia and Analgesia, 19.04.2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The Association Between Preoperative Frailty and Postoperative Delirium After Cardiac Surgery
AU - Brown, Charles
AU - Max, Laura
AU - LaFlam, Andrew
AU - Kirk, Lou
AU - Gross, Alden L
AU - Arora, Rakesh
AU - Neufeld, Karin Jane
AU - Hogue, Charles W.
AU - Walston, Jeremy D
AU - Pustavoitau, Aliaksei
PY - 2016/4/19
Y1 - 2016/4/19
N2 - Delirium is common after cardiac surgery, and preoperative identification of high-risk patients could guide prevention strategies. We prospectively measured frailty in 55 patients before cardiac surgery and assessed postoperative delirium using a validated chart review. The prevalence of frailty was 30.9%. Frail patients had a higher incidence of delirium (47.1%) compared with nonfrail patients (2.6%; P <0.001). In multivariable models, the relative risk of delirium was ≥2.1-fold greater in frail compared with nonfrail patients (relative risk, 18.3; 95% confidence interval, 2.1–161.8; P = 0.009). Frailty may identify patients who would benefit from delirium-prevention strategies because of increased baseline risk for delirium.
AB - Delirium is common after cardiac surgery, and preoperative identification of high-risk patients could guide prevention strategies. We prospectively measured frailty in 55 patients before cardiac surgery and assessed postoperative delirium using a validated chart review. The prevalence of frailty was 30.9%. Frail patients had a higher incidence of delirium (47.1%) compared with nonfrail patients (2.6%; P <0.001). In multivariable models, the relative risk of delirium was ≥2.1-fold greater in frail compared with nonfrail patients (relative risk, 18.3; 95% confidence interval, 2.1–161.8; P = 0.009). Frailty may identify patients who would benefit from delirium-prevention strategies because of increased baseline risk for delirium.
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U2 - 10.1213/ANE.0000000000001271
DO - 10.1213/ANE.0000000000001271
M3 - Article
JO - Anesthesia and Analgesia
JF - Anesthesia and Analgesia
SN - 0003-2999
ER -