Abstract
Context Pain is a common problem in patients with cystic fibrosis (CF) and in adults is associated with lower quality of life and more pulmonary complications. Less is known about the impact of pain in adolescents with CF. Objectives This study aimed to describe pain in an adolescent CF population and to determine if pain at baseline is associated with lower health-related quality of life (HRQoL) and worse pulmonary outcomes at six-month follow-up. Methods We administered surveys at baseline and at six months to CF patients aged 12 to 20 years. Analyses included Wilcoxon log-rank tests, Spearman correlations, and linear and logistic regressions. Results Seventy-three patients (86.9%) completed the baseline questionnaire and 53 patients (63.1%) completed the six-month follow-up questionnaire. Mean age was 15.6 ± 2.5 and mean FEV1 was 79 ± 26% predicted; 89% of patients reported pain in the three months before the survey, but in most it was short lived and mild to moderate in severity. Abdominal pain was the most common location. Pain was associated with increased pulmonary exacerbations (odds ratios = 1.99 for every one-point increase on a composite pain scale, P = 0.03) and with lower HRQoL. Conclusions Pain in adolescents with CF is associated with lower HRQoL and more pulmonary exacerbations. Greater efforts are needed to manage pain in this population and to determine if treatment of pain improves other outcomes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 681-687 |
| Number of pages | 7 |
| Journal | Journal of Pain and Symptom Management |
| Volume | 52 |
| Issue number | 5 |
| DOIs | |
| State | Published - Nov 1 2016 |
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Keywords
- Cystic fibrosis
- pain
- quality of life
ASJC Scopus subject areas
- Nursing(all)
- Clinical Neurology
- Anesthesiology and Pain Medicine
Cite this
The Association Between Pain and Clinical Outcomes in Adolescents With Cystic Fibrosis. / Lechtzin, Noah; Allgood, Sarah; Hong, Gina; Riekert, Kristin; Haythornthwaite, Jennifer A.; Mogayzel, Peter; Hankinson, Jessica Curley; Yaster, Myron.
In: Journal of Pain and Symptom Management, Vol. 52, No. 5, 01.11.2016, p. 681-687.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The Association Between Pain and Clinical Outcomes in Adolescents With Cystic Fibrosis
AU - Lechtzin, Noah
AU - Allgood, Sarah
AU - Hong, Gina
AU - Riekert, Kristin
AU - Haythornthwaite, Jennifer A.
AU - Mogayzel, Peter
AU - Hankinson, Jessica Curley
AU - Yaster, Myron
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Context Pain is a common problem in patients with cystic fibrosis (CF) and in adults is associated with lower quality of life and more pulmonary complications. Less is known about the impact of pain in adolescents with CF. Objectives This study aimed to describe pain in an adolescent CF population and to determine if pain at baseline is associated with lower health-related quality of life (HRQoL) and worse pulmonary outcomes at six-month follow-up. Methods We administered surveys at baseline and at six months to CF patients aged 12 to 20 years. Analyses included Wilcoxon log-rank tests, Spearman correlations, and linear and logistic regressions. Results Seventy-three patients (86.9%) completed the baseline questionnaire and 53 patients (63.1%) completed the six-month follow-up questionnaire. Mean age was 15.6 ± 2.5 and mean FEV1 was 79 ± 26% predicted; 89% of patients reported pain in the three months before the survey, but in most it was short lived and mild to moderate in severity. Abdominal pain was the most common location. Pain was associated with increased pulmonary exacerbations (odds ratios = 1.99 for every one-point increase on a composite pain scale, P = 0.03) and with lower HRQoL. Conclusions Pain in adolescents with CF is associated with lower HRQoL and more pulmonary exacerbations. Greater efforts are needed to manage pain in this population and to determine if treatment of pain improves other outcomes.
AB - Context Pain is a common problem in patients with cystic fibrosis (CF) and in adults is associated with lower quality of life and more pulmonary complications. Less is known about the impact of pain in adolescents with CF. Objectives This study aimed to describe pain in an adolescent CF population and to determine if pain at baseline is associated with lower health-related quality of life (HRQoL) and worse pulmonary outcomes at six-month follow-up. Methods We administered surveys at baseline and at six months to CF patients aged 12 to 20 years. Analyses included Wilcoxon log-rank tests, Spearman correlations, and linear and logistic regressions. Results Seventy-three patients (86.9%) completed the baseline questionnaire and 53 patients (63.1%) completed the six-month follow-up questionnaire. Mean age was 15.6 ± 2.5 and mean FEV1 was 79 ± 26% predicted; 89% of patients reported pain in the three months before the survey, but in most it was short lived and mild to moderate in severity. Abdominal pain was the most common location. Pain was associated with increased pulmonary exacerbations (odds ratios = 1.99 for every one-point increase on a composite pain scale, P = 0.03) and with lower HRQoL. Conclusions Pain in adolescents with CF is associated with lower HRQoL and more pulmonary exacerbations. Greater efforts are needed to manage pain in this population and to determine if treatment of pain improves other outcomes.
KW - Cystic fibrosis
KW - pain
KW - quality of life
UR - http://www.scopus.com/inward/record.url?scp=84995663185&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84995663185&partnerID=8YFLogxK
U2 - 10.1016/j.jpainsymman.2016.03.023
DO - 10.1016/j.jpainsymman.2016.03.023
M3 - Article
C2 - 27693896
AN - SCOPUS:84995663185
VL - 52
SP - 681
EP - 687
JO - Journal of Pain and Symptom Management
JF - Journal of Pain and Symptom Management
SN - 0885-3924
IS - 5
ER -