The Association Between Lipoproteins, Disability, and Physical Function Among Older Costa Rican Adults

Marianne Chanti-Ketterl, Alyssa Gamaldo, Ross Andel, Roland J. Thorpe

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To examine the relationship between total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C) with disability and physical performance. Method: Wave 1 data were from Costa Rican Longevity and Healthy Aging Study (n = 2,827). Lipoprotein profiles were measured using blood samples. Disability and physical functioning were measured with activities of daily living/instrumental activities of daily living (ADLs/IADLs) and objective assessment of physical performance. Results: Lower HDL-C was associated with greater ADL disability, and lower TC with longer time to pick-a-pencil and Time-Up-Go (TUG) test. Age interacted between (a) TG and lung function, chair stands, and pick-a-pencil, and (b) HDL-C and TUG. Stratification showed lower TG and longer time picking up a pencil only for those above 84 years. Based on significant interactions with sex, lower TC was associated with slower chair stand time in women and higher HDL-C with slower chair stand time in men. Discussion: Lower levels of lipoproteins may suggest worse physical function, but the association may differ by sex.

Original languageEnglish (US)
Pages (from-to)758-777
Number of pages20
JournalJournal of Aging and Health
Volume30
Issue number5
DOIs
StatePublished - Jun 1 2018

Keywords

  • Hispanics
  • Latin America
  • biomarkers
  • frailty

ASJC Scopus subject areas

  • Health(social science)
  • Sociology and Political Science
  • Life-span and Life-course Studies

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