The ARP2/3 complex: An actin nucleator comes of age

Erin D. Goley; Matthew D. Welch

doi:10.1038/nrm2026

The ARP2/3 complex: An actin nucleator comes of age

Research output: Contribution to journal › Review article › peer-review

Abstract

The cellular functions of the actin cytoskeleton require precise regulation of both the initiation of actin polymerization and the organization of the resulting filaments. The actin-related protein-2/3 (ARP2/3) complex is a central player in this regulation. A decade of study has begun to shed light on the molecular mechanisms by which this powerful machine controls the polymerization, organization and recycling of actin-filament networks, both in vitro and in the living cell.

Original language	English (US)
Pages (from-to)	713-726
Number of pages	14
Journal	Nature Reviews Molecular Cell Biology
Volume	7
Issue number	10
DOIs	https://doi.org/10.1038/nrm2026
State	Published - Oct 23 2006
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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