The aquaporin family of water channels in kidney

An update on physiology and pathophysiology of aquaporin-2

Søren Nielsen, David Marples, Jørgen Frøkiær, Mark Knepper, Peter C Agre

Research output: Contribution to journalArticle

Abstract

The long-standing problem of membrane water transport has been advanced by the recognition of a new family of water transport proteins, the 'aquaporins'. Not surprisingly, water transport is a major process in kidney physiology, and the biology of aquaporins is most thoroughly understood in that organ. We reviewed in detail the status of aquaporins in the kidney only one year ago, but the subsequent progress has dictated the need for an update. This seems especially appropriate in honor of the 100th birthday of Homer Smith, the pioneer whose foresight initiated this field.

Original languageEnglish (US)
Pages (from-to)1718-1723
Number of pages6
JournalKidney International
Volume49
Issue number6
StatePublished - 1996
Externally publishedYes

Fingerprint

Aquaporin 2
Aquaporins
Kidney
Water
Carrier Proteins
Membranes

ASJC Scopus subject areas

  • Nephrology

Cite this

The aquaporin family of water channels in kidney : An update on physiology and pathophysiology of aquaporin-2. / Nielsen, Søren; Marples, David; Frøkiær, Jørgen; Knepper, Mark; Agre, Peter C.

In: Kidney International, Vol. 49, No. 6, 1996, p. 1718-1723.

Research output: Contribution to journalArticle

Nielsen, Søren ; Marples, David ; Frøkiær, Jørgen ; Knepper, Mark ; Agre, Peter C. / The aquaporin family of water channels in kidney : An update on physiology and pathophysiology of aquaporin-2. In: Kidney International. 1996 ; Vol. 49, No. 6. pp. 1718-1723.
@article{087340428fa2460988b692b723e79e16,
title = "The aquaporin family of water channels in kidney: An update on physiology and pathophysiology of aquaporin-2",
abstract = "The long-standing problem of membrane water transport has been advanced by the recognition of a new family of water transport proteins, the 'aquaporins'. Not surprisingly, water transport is a major process in kidney physiology, and the biology of aquaporins is most thoroughly understood in that organ. We reviewed in detail the status of aquaporins in the kidney only one year ago, but the subsequent progress has dictated the need for an update. This seems especially appropriate in honor of the 100th birthday of Homer Smith, the pioneer whose foresight initiated this field.",
author = "S{\o}ren Nielsen and David Marples and J{\o}rgen Fr{\o}ki{\ae}r and Mark Knepper and Agre, {Peter C}",
year = "1996",
language = "English (US)",
volume = "49",
pages = "1718--1723",
journal = "Kidney International",
issn = "0085-2538",
publisher = "Nature Publishing Group",
number = "6",

}

TY - JOUR

T1 - The aquaporin family of water channels in kidney

T2 - An update on physiology and pathophysiology of aquaporin-2

AU - Nielsen, Søren

AU - Marples, David

AU - Frøkiær, Jørgen

AU - Knepper, Mark

AU - Agre, Peter C

PY - 1996

Y1 - 1996

N2 - The long-standing problem of membrane water transport has been advanced by the recognition of a new family of water transport proteins, the 'aquaporins'. Not surprisingly, water transport is a major process in kidney physiology, and the biology of aquaporins is most thoroughly understood in that organ. We reviewed in detail the status of aquaporins in the kidney only one year ago, but the subsequent progress has dictated the need for an update. This seems especially appropriate in honor of the 100th birthday of Homer Smith, the pioneer whose foresight initiated this field.

AB - The long-standing problem of membrane water transport has been advanced by the recognition of a new family of water transport proteins, the 'aquaporins'. Not surprisingly, water transport is a major process in kidney physiology, and the biology of aquaporins is most thoroughly understood in that organ. We reviewed in detail the status of aquaporins in the kidney only one year ago, but the subsequent progress has dictated the need for an update. This seems especially appropriate in honor of the 100th birthday of Homer Smith, the pioneer whose foresight initiated this field.

UR - http://www.scopus.com/inward/record.url?scp=0030007744&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030007744&partnerID=8YFLogxK

M3 - Article

VL - 49

SP - 1718

EP - 1723

JO - Kidney International

JF - Kidney International

SN - 0085-2538

IS - 6

ER -