The aquaporin family of membrane water channels

Andreas Engel, Thomas Walz, Peter C Agre

Research output: Contribution to journalArticle

Abstract

The rapid movement of water across the plasma membranes of certain cells has been a long-standing puzzle to membrane biophysicists and physiologists; the discovery of the red cell channel-forming integral protein has provided a molecular solution to this puzzle. The identification of this protein has led to the recognition of a family of related water-selective channels, the aquaporins, that are found in animals, plants and microbial organisms. In order to provide insight into the remarkable but simple function of these membrane proteins, their structures are being elucidated.

Original languageEnglish (US)
Pages (from-to)545-553
Number of pages9
JournalCurrent Opinion in Structural Biology
Volume4
Issue number4
DOIs
StatePublished - 1994

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Aquaporins
Ion Channels
Water Movements
Membrane Proteins
Proteins
Cell Membrane
Membranes

ASJC Scopus subject areas

  • Molecular Biology
  • Structural Biology

Cite this

The aquaporin family of membrane water channels. / Engel, Andreas; Walz, Thomas; Agre, Peter C.

In: Current Opinion in Structural Biology, Vol. 4, No. 4, 1994, p. 545-553.

Research output: Contribution to journalArticle

Engel, Andreas ; Walz, Thomas ; Agre, Peter C. / The aquaporin family of membrane water channels. In: Current Opinion in Structural Biology. 1994 ; Vol. 4, No. 4. pp. 545-553.
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