The apoptosome at high resolution

Xinchen Teng, J Marie Hardwick

Research output: Contribution to journalArticle

Abstract

The mechanism by which the apoptosome activates caspases during apoptosis has been controversial. Qi et al. (2010) now present a crystal structure of a funnel-shaped octameric apoptosome complex from the nematode Caenorhabditis elegans that challenges currently held assumptions about the human apoptosome structure.

Original languageEnglish (US)
Pages (from-to)402-404
Number of pages3
JournalCell
Volume141
Issue number3
DOIs
StatePublished - Apr 2010

Fingerprint

Apoptosomes
Caspases
Crystal structure
Apoptosis
Qi
Caenorhabditis elegans

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

The apoptosome at high resolution. / Teng, Xinchen; Hardwick, J Marie.

In: Cell, Vol. 141, No. 3, 04.2010, p. 402-404.

Research output: Contribution to journalArticle

Teng, Xinchen ; Hardwick, J Marie. / The apoptosome at high resolution. In: Cell. 2010 ; Vol. 141, No. 3. pp. 402-404.
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