Abstract
The mechanism by which the apoptosome activates caspases during apoptosis has been controversial. Qi et al. (2010) now present a crystal structure of a funnel-shaped octameric apoptosome complex from the nematode Caenorhabditis elegans that challenges currently held assumptions about the human apoptosome structure.
Original language | English (US) |
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Pages (from-to) | 402-404 |
Number of pages | 3 |
Journal | Cell |
Volume | 141 |
Issue number | 3 |
DOIs | |
State | Published - Apr 2010 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology