The apoptosome at high resolution

Xinchen Teng, J. Marie Hardwick

Research output: Contribution to journalShort survey


The mechanism by which the apoptosome activates caspases during apoptosis has been controversial. Qi et al. (2010) now present a crystal structure of a funnel-shaped octameric apoptosome complex from the nematode Caenorhabditis elegans that challenges currently held assumptions about the human apoptosome structure.

Original languageEnglish (US)
Pages (from-to)402-404
Number of pages3
Issue number3
StatePublished - Apr 1 2010

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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