The age of the Arabidopsis thaliana genome duplication

Maria D. Ermolaeva; Martin Wu; Jonathan A. Eisen; Steven L. Salzberg

doi:10.1023/A:1023001130337

The age of the Arabidopsis thaliana genome duplication

Maria D. Ermolaeva, Martin Wu, Jonathan A. Eisen, Steven L. Salzberg

Research output: Contribution to journal › Article › peer-review

86 Scopus citations

Abstract

We estimate the timing of the Arabidopsis thaliana whole-genome duplication by means of phylogenetic and statistical analysis, and propose two possible scenarios for the duplication. The first one, based on the assumption that the duplicated segments diverged from an autotetraploid form, places the duplication at about 38 million years ago, after the Arabidopsis lineage diverged from that of soybean (Glycine max) and before it diverged from its sister genus, Brassica. The second scenario assumes that the ancestor was allotetraploid, and suggests that the duplication is younger than 38 million years and may have contributed to the Arabidopsis-Brassica divergence. In each case, our estimate places the age of the genome duplication as significantly younger than previously reported.

Original language	English (US)
Pages (from-to)	859-866
Number of pages	8
Journal	Plant Molecular Biology
Volume	51
Issue number	6
DOIs	https://doi.org/10.1023/A:1023001130337
State	Published - Apr 2003
Externally published	Yes

Keywords

Arabidopsis
Bioinformatics
Evolution
Gene loss
Genome duplication

ASJC Scopus subject areas

Agronomy and Crop Science
Genetics
Plant Science

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10.1023/A:1023001130337

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title = "The age of the Arabidopsis thaliana genome duplication",

abstract = "We estimate the timing of the Arabidopsis thaliana whole-genome duplication by means of phylogenetic and statistical analysis, and propose two possible scenarios for the duplication. The first one, based on the assumption that the duplicated segments diverged from an autotetraploid form, places the duplication at about 38 million years ago, after the Arabidopsis lineage diverged from that of soybean (Glycine max) and before it diverged from its sister genus, Brassica. The second scenario assumes that the ancestor was allotetraploid, and suggests that the duplication is younger than 38 million years and may have contributed to the Arabidopsis-Brassica divergence. In each case, our estimate places the age of the genome duplication as significantly younger than previously reported.",

keywords = "Arabidopsis, Bioinformatics, Evolution, Gene loss, Genome duplication",

author = "Ermolaeva, {Maria D.} and Martin Wu and Eisen, {Jonathan A.} and Salzberg, {Steven L.}",

note = "Funding Information: We would like to thank Chris Town and Brian Haas for useful discussions and comments. M.D.E., M.W., and S.L.S. were supported in part by National Science Foundation grant KDI-9980088, S.L.S. was partly supported by NIH grant R01-LM06845, and M.D.E. was partly supported by NSF Cooperative Agreement DBI 98-13586.",

year = "2003",

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doi = "10.1023/A:1023001130337",

language = "English (US)",

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T1 - The age of the Arabidopsis thaliana genome duplication

AU - Ermolaeva, Maria D.

AU - Wu, Martin

AU - Eisen, Jonathan A.

AU - Salzberg, Steven L.

N1 - Funding Information: We would like to thank Chris Town and Brian Haas for useful discussions and comments. M.D.E., M.W., and S.L.S. were supported in part by National Science Foundation grant KDI-9980088, S.L.S. was partly supported by NIH grant R01-LM06845, and M.D.E. was partly supported by NSF Cooperative Agreement DBI 98-13586.

PY - 2003/4

Y1 - 2003/4

N2 - We estimate the timing of the Arabidopsis thaliana whole-genome duplication by means of phylogenetic and statistical analysis, and propose two possible scenarios for the duplication. The first one, based on the assumption that the duplicated segments diverged from an autotetraploid form, places the duplication at about 38 million years ago, after the Arabidopsis lineage diverged from that of soybean (Glycine max) and before it diverged from its sister genus, Brassica. The second scenario assumes that the ancestor was allotetraploid, and suggests that the duplication is younger than 38 million years and may have contributed to the Arabidopsis-Brassica divergence. In each case, our estimate places the age of the genome duplication as significantly younger than previously reported.

AB - We estimate the timing of the Arabidopsis thaliana whole-genome duplication by means of phylogenetic and statistical analysis, and propose two possible scenarios for the duplication. The first one, based on the assumption that the duplicated segments diverged from an autotetraploid form, places the duplication at about 38 million years ago, after the Arabidopsis lineage diverged from that of soybean (Glycine max) and before it diverged from its sister genus, Brassica. The second scenario assumes that the ancestor was allotetraploid, and suggests that the duplication is younger than 38 million years and may have contributed to the Arabidopsis-Brassica divergence. In each case, our estimate places the age of the genome duplication as significantly younger than previously reported.

KW - Arabidopsis

KW - Bioinformatics

KW - Evolution

KW - Gene loss

KW - Genome duplication

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JO - Plant Molecular Biology

JF - Plant Molecular Biology

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The age of the Arabidopsis thaliana genome duplication

Abstract

Keywords

ASJC Scopus subject areas

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