The activation of Lymphocytes is in their CARMA

Abul K. Abbas, Ranjan Sen

Research output: Contribution to journalArticle

Abstract

Lymphocyte activation via antigen receptors initiates adaptive immune responses. Two papers in this issue of Immunity demonstrate that CARMA-1, a CARD carrying member of the MAGUK family proteins, is essential for lymphocyte activation. CARMA-1 functions by coupling antigen receptor signals to NF-κB induction and JNK activation.

Original languageEnglish (US)
Pages (from-to)721-722
Number of pages2
JournalImmunity
Volume18
Issue number6
DOIs
StatePublished - Jun 1 2003
Externally publishedYes

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Antigen Receptors
Lymphocyte Activation
Guanylate Kinases
Adaptive Immunity
Immunity

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases
  • Immunology

Cite this

The activation of Lymphocytes is in their CARMA. / Abbas, Abul K.; Sen, Ranjan.

In: Immunity, Vol. 18, No. 6, 01.06.2003, p. 721-722.

Research output: Contribution to journalArticle

Abbas, Abul K. ; Sen, Ranjan. / The activation of Lymphocytes is in their CARMA. In: Immunity. 2003 ; Vol. 18, No. 6. pp. 721-722.
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