The action of Lipoxin-A on glomerular microcirculatory dynamics in the rat

Kamal F. Badr; Charles N. Serhan; K. C. Nicolaou; Bengt Samuelsson

doi:10.1016/0006-291X(87)91337-4

The action of Lipoxin-A on glomerular microcirculatory dynamics in the rat

Kamal F. Badr, Charles N. Serhan, K. C. Nicolaou, Bengt Samuelsson

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Intrarenal administration of 750 ng/kg/min of LX-A in euvolemic rats resulted in significant increases in single nephron GFR (38.4±1.7 to 45.5±3.0 nl/min) and plasma flow rate (95±6 to 127±9 nl/min). The latter was due to a dramatic fall in afferent arteriolar resistance. Mean transcapillary hydraulic pressure difference increased from 33±1 to 43±3 mmHg (p

Original language	English (US)
Pages (from-to)	408-414
Number of pages	7
Journal	Biochemical and Biophysical Research Communications
Volume	145
Issue number	1
DOIs	https://doi.org/10.1016/0006-291X(87)91337-4
State	Published - May 29 1987
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Biophysics
Molecular Biology

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abstract = "Intrarenal administration of 750 ng/kg/min of LX-A in euvolemic rats resulted in significant increases in single nephron GFR (38.4±1.7 to 45.5±3.0 nl/min) and plasma flow rate (95±6 to 127±9 nl/min). The latter was due to a dramatic fall in afferent arteriolar resistance. Mean transcapillary hydraulic pressure difference increased from 33±1 to 43±3 mmHg (p",

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AB - Intrarenal administration of 750 ng/kg/min of LX-A in euvolemic rats resulted in significant increases in single nephron GFR (38.4±1.7 to 45.5±3.0 nl/min) and plasma flow rate (95±6 to 127±9 nl/min). The latter was due to a dramatic fall in afferent arteriolar resistance. Mean transcapillary hydraulic pressure difference increased from 33±1 to 43±3 mmHg (p

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The action of Lipoxin-A on glomerular microcirculatory dynamics in the rat

Abstract

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