Testosterone: effect on rat testis

P. C. Walsh, R. S. Swerdloff

Research output: Contribution to journalArticlepeer-review


Testosterone (T) in low doses exerts its effects on the testis by suppressing serum luteinizing hormone (LH) and subsequent Leydig cell secretion of T, thereby producing a decrease in the high intratesticular concentrations of T which are necessary for maintenance of the germinal epithelium. High dose T, although suppressing both LH and follicle stimulating hormone (FSH), provides circulating levels of T sufficiently high (producing a threefold increase in ventral prostate weight) to maintain the germinal epithelium.

Original languageEnglish (US)
Pages (from-to)522-523
Number of pages2
JournalSurgical forum
VolumeVOL. 23
StatePublished - Jan 1 1972
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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