Testosterone (T) in low doses exerts its effects on the testis by suppressing serum luteinizing hormone (LH) and subsequent Leydig cell secretion of T, thereby producing a decrease in the high intratesticular concentrations of T which are necessary for maintenance of the germinal epithelium. High dose T, although suppressing both LH and follicle stimulating hormone (FSH), provides circulating levels of T sufficiently high (producing a threefold increase in ventral prostate weight) to maintain the germinal epithelium.
|Original language||English (US)|
|Number of pages||2|
|State||Published - Jan 1 1972|
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