Testosterone and depressive symptoms among men in the Diabetes Prevention Program

on behalf of the Diabetes Prevention Program Research Group

Research output: Contribution to journalArticle

Abstract

Objective We examined associations between intensive lifestyle intervention (ILS) and changes in testosterone and associations with mood among middle-aged men. Design Secondary analysis of men (n = 886) participating in the Diabetes Prevention Program which randomized glucose-intolerant, overweight men to ILS, metformin, or placebo between 1996 and 1999. Main outcome measures Changes in testosterone between baseline and 1-year follow-up asnd associations of these changes with mood measures (Beck Depression Inventory [BDI-II], Beck Anxiety Inventory [BAI]). Results Median baseline testosterone was 10.98 nmol/l and 44% (n = 385) had testosterone 

Original languageEnglish (US)
Pages (from-to)63-71
Number of pages9
JournalPsychoneuroendocrinology
Volume72
DOIs
StatePublished - Oct 1 2016

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Testosterone
Depression
Life Style
Equipment and Supplies
Metformin
Anxiety
Placebos
Outcome Assessment (Health Care)
Glucose

Keywords

  • Androgens
  • Glucose-intolerance
  • Mood
  • Testosterone

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Endocrine and Autonomic Systems

Cite this

Testosterone and depressive symptoms among men in the Diabetes Prevention Program. / on behalf of the Diabetes Prevention Program Research Group.

In: Psychoneuroendocrinology, Vol. 72, 01.10.2016, p. 63-71.

Research output: Contribution to journalArticle

on behalf of the Diabetes Prevention Program Research Group. / Testosterone and depressive symptoms among men in the Diabetes Prevention Program. In: Psychoneuroendocrinology. 2016 ; Vol. 72. pp. 63-71.
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AB - Objective We examined associations between intensive lifestyle intervention (ILS) and changes in testosterone and associations with mood among middle-aged men. Design Secondary analysis of men (n = 886) participating in the Diabetes Prevention Program which randomized glucose-intolerant, overweight men to ILS, metformin, or placebo between 1996 and 1999. Main outcome measures Changes in testosterone between baseline and 1-year follow-up asnd associations of these changes with mood measures (Beck Depression Inventory [BDI-II], Beck Anxiety Inventory [BAI]). Results Median baseline testosterone was 10.98 nmol/l and 44% (n = 385) had testosterone 

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