@article{64e6ab41c88849e89f5724d544169919,
title = "Testing gene by community disadvantage moderation of sexual health outcomes among urban women",
abstract = "We examined whether the interplay between community disadvantage and a conduct disorder polygenic risk score (CD PRS) was associated with sexual health outcomes among urban women. Participants (N = 511; 75.5% African American) were originally recruited to participate in a school-based intervention and were followed into adulthood. Community disadvantage was calculated using census data when participants were in first grade. At age 20, blood or saliva samples were collected and participants reported on their condom use, sexual partners, and sexually transmitted infections. A CD PRS was created based on a genome-wide association study conducted by Dick et al. [2010]. Higher levels of community disadvantage was associated with greater sexually transmitted infections among women with a higher CD PRS. Implications of the study findings are discussed.",
author = "Powell, {Terrinieka W.} and Rabinowitz, {Jill A.} and Kaufman, {Michelle R.} and Milam, {Adam J.} and Kelly Benke and Sisto, {Danielle Y.} and George Uhl and Maher, {Brion S.} and Ialongo, {Nicholas S.}",
note = "Funding Information: This work was funded by the Maternal and Child Health Bureau (T76MC00003; T.P), the National Institute on Drug Abuse (1K01DA042134-01A1 – T.P., 1K01DA042138-01A1 (M.K), T32DA007292 (J.A.R), R01DA036525 (B.S.M), DA11796 MH57005 (N.S.I), R01 DA009897 (W.E), R01 MH 4296806 (S.K.), the National Institute of Mental Health (R25MH080665 -T.P.) and the Centers for Disease Control and Prevention (Grant #1-U48-DP-000040 – T.P.). Publisher Copyright: {\textcopyright} 2019 Powell et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.",
year = "2019",
month = oct,
day = "1",
doi = "10.1371/journal.pone.0223311",
language = "English (US)",
volume = "14",
journal = "PloS one",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "10",
}