Testicular juvenile granulosa cell tumor in a newborn: Case report and review of the literature

Borislav A. Alexiev, Samuel M. Alaish, Chen Chih Sun

Research output: Contribution to journalArticle

Abstract

Juvenile granulosa cell tumor of the testis of neonates and infants is an uncommon lesion frequently associated with abnormal sex chromosome and ambiguous genitalia. This report describes a juvenile granulosa cell tumor arising in the testis of a neonate. Chromosome analysis of the tumor showed a normal male karyotype 46 XY. Histopathology and immunohistochemical studies revealed the occurrence of 2 well-differentiated epithelial-like and smooth muscle-like components in the neoplasm. The morphologic clues leading to the correct diagnosis of juvenile granulosa cell tumor and the possible histogenesis are briefly discussed.

Original languageEnglish (US)
Pages (from-to)321-325
Number of pages5
JournalInternational Journal of Surgical Pathology
Volume15
Issue number3
DOIs
StatePublished - Jul 2007
Externally publishedYes

Fingerprint

Granulosa Cell Tumor
Newborn Infant
Testis
Disorders of Sex Development
Sex Chromosomes
Karyotype
Smooth Muscle
Neoplasms
Chromosomes

Keywords

  • Juvenile granulosae cell tumor
  • Neonate
  • Testis

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine
  • Surgery

Cite this

Testicular juvenile granulosa cell tumor in a newborn : Case report and review of the literature. / Alexiev, Borislav A.; Alaish, Samuel M.; Sun, Chen Chih.

In: International Journal of Surgical Pathology, Vol. 15, No. 3, 07.2007, p. 321-325.

Research output: Contribution to journalArticle

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