Testicular juvenile granulosa cell tumor in a newborn: Case report and review of the literature

Borislav A. Alexiev, Samuel M. Alaish, Chen Chih Sun

Research output: Contribution to journalArticlepeer-review

Abstract

Juvenile granulosa cell tumor of the testis of neonates and infants is an uncommon lesion frequently associated with abnormal sex chromosome and ambiguous genitalia. This report describes a juvenile granulosa cell tumor arising in the testis of a neonate. Chromosome analysis of the tumor showed a normal male karyotype 46 XY. Histopathology and immunohistochemical studies revealed the occurrence of 2 well-differentiated epithelial-like and smooth muscle-like components in the neoplasm. The morphologic clues leading to the correct diagnosis of juvenile granulosa cell tumor and the possible histogenesis are briefly discussed.

Original languageEnglish (US)
Pages (from-to)321-325
Number of pages5
JournalInternational journal of surgical pathology
Volume15
Issue number3
DOIs
StatePublished - Jul 1 2007
Externally publishedYes

Keywords

  • Juvenile granulosae cell tumor
  • Neonate
  • Testis

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine

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