TY - JOUR
T1 - Test for Respiratory and Asthma Control in Kids (TRACK)
T2 - A caregiver-completed questionnaire for preschool-aged children
AU - Murphy, Kevin R.
AU - Zeiger, Robert S.
AU - Kosinski, Mark
AU - Chipps, Bradley
AU - Mellon, Michael
AU - Schatz, Michael
AU - Lampl, Kathy
AU - Hanlon, Jennifer T.
AU - Ramachandran, Sulabha
N1 - Funding Information:
We thank Joseph Spahn (Denver, Colo) for his invaluable contributions to the design of the study and interpretation of the data. We also acknowledge the efforts of the physicians who participated in this study: William E. Berger (Mission Viejo, Calif), Michael Blaiss (Germantown, Tenn), Randall Brown (Atlanta, Ga), Don Bukstein (Madison, Wis), John Calcagno (Gresham, Ore), Stuart Cohen (San Diego, Calif), Marc Goldstein (Philadelphia, Pa), William Hitchcock (La Jolla, Calif), Michael Lawrence (Taunton, Mass), Todd Mahr (La Crosse, Wis), John Matz (Baltimore, Md), Nancy K. Ostrom (San Diego, Calif), Michael Pichichero (Rochester, NY), Shelley Senders (Cleveland, Ohio), Shailen Shah (Collegeville, Pa), Timothy Sullivan (Norwich, Conn), and Steven Weinstein (Huntington Beach, Calif). Finally, we thank Marissa Buttaro, MPH, from Scientific Connexions (Newtown, Pa) for editorial assistance funded by AstraZeneca LP.
PY - 2009/4
Y1 - 2009/4
N2 - Background: A validated questionnaire is needed to monitor respiratory control in preschool-aged children. Objective: We sought to develop and validate a caregiver-completed questionnaire that measures respiratory control in young children. Methods: A 33-item questionnaire that included asthma impairment and risk items was administered to 486 caregivers of children aged younger than 5 years with a current, recent, or past history of respiratory symptoms. Stepwise regression was used to select a subset of items with the greatest discriminant validity in relation to guidelines-defined asthma control in a random two-thirds development sample. Reliability, validity, and ability to screen for respiratory control problems were tested in development and validation samples (remaining one-third sample). Results: The content of the 5 items selected, the Test for Respiratory and Asthma Control in Kids (TRACK), included frequency of respiratory symptoms (wheeze, cough, shortness of breath), activity limitation, and nighttime awakenings in the past 4 weeks; rescue medication use in the past 3 months; and oral corticosteroid use in the previous year. Reliability was greater than 0.70 in both samples. ANOVA showed that mean scores differed significantly (P < .001) in the expected direction across both samples for 3 levels of guidelines-based respiratory control, physician-recommended change in therapy, and symptom status. In the development and validation samples, screening analyses revealed areas under the receiver operating characteristic curve of 0.88 and 0.82, respectively; control status was correctly classified in 81% and 78% of cases. Conclusion: TRACK is a valid, easy-to-administer, caregiver-completed questionnaire of respiratory control in preschool-aged children with symptoms consistent with asthma.
AB - Background: A validated questionnaire is needed to monitor respiratory control in preschool-aged children. Objective: We sought to develop and validate a caregiver-completed questionnaire that measures respiratory control in young children. Methods: A 33-item questionnaire that included asthma impairment and risk items was administered to 486 caregivers of children aged younger than 5 years with a current, recent, or past history of respiratory symptoms. Stepwise regression was used to select a subset of items with the greatest discriminant validity in relation to guidelines-defined asthma control in a random two-thirds development sample. Reliability, validity, and ability to screen for respiratory control problems were tested in development and validation samples (remaining one-third sample). Results: The content of the 5 items selected, the Test for Respiratory and Asthma Control in Kids (TRACK), included frequency of respiratory symptoms (wheeze, cough, shortness of breath), activity limitation, and nighttime awakenings in the past 4 weeks; rescue medication use in the past 3 months; and oral corticosteroid use in the previous year. Reliability was greater than 0.70 in both samples. ANOVA showed that mean scores differed significantly (P < .001) in the expected direction across both samples for 3 levels of guidelines-based respiratory control, physician-recommended change in therapy, and symptom status. In the development and validation samples, screening analyses revealed areas under the receiver operating characteristic curve of 0.88 and 0.82, respectively; control status was correctly classified in 81% and 78% of cases. Conclusion: TRACK is a valid, easy-to-administer, caregiver-completed questionnaire of respiratory control in preschool-aged children with symptoms consistent with asthma.
KW - Asthma
KW - TRACK
KW - asthma control
KW - asthma guidelines
KW - respiratory symptoms
KW - validated questionnaire
KW - young children
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U2 - 10.1016/j.jaci.2009.01.058
DO - 10.1016/j.jaci.2009.01.058
M3 - Article
C2 - 19348922
AN - SCOPUS:63749083136
SN - 0091-6749
VL - 123
SP - 833-839.e9
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
IS - 4
ER -