Termination of malignant ventricular arrhythmias with an implanted automatic defibrillator in human beings

M. Mirowski, P. R. Reid, Morton Maimon Mower, L. Watkins, Vincent L Gott, J. F. Schauble, A. Langer, M. S. Heilman, S. A. Kolenik, R. E. Fischell, Myron Weisfeldt

Research output: Contribution to journalArticle

Abstract

The development of a clinically applicable, automatic, implantable defibrillator has been described previously. This electronic device is designed to monitor cardiac electrical activity, to recognize ventricular fibrillation and ventricular tachyarrhythmias with a sinusoidal wave form, and then to deliver corrective defibrillatory discharges. It is intended to protect patients at particularly high risk of sudden death whenever and wherever they are stricken by these lethal arrhythmias. After extensive preclinical testing, a pilot study of this new technique was recently intiated at the Johns Hopkins Hospital. This article describes the first three patients in whom the automatic defibrillator was implanted to manage recurrent ventricular tachyarrhythmias that were refractory to medical therapy. Our results suggest that the device can successfully identify and reverse these malignant arrhythmias in human beings.

Original languageEnglish (US)
Pages (from-to)322-324
Number of pages3
JournalNew England Journal of Medicine
Volume303
Issue number6
StatePublished - 1980

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Defibrillators
Tachycardia
Cardiac Arrhythmias
Equipment and Supplies
Implantable Defibrillators
Ventricular Fibrillation
Sudden Death
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Termination of malignant ventricular arrhythmias with an implanted automatic defibrillator in human beings. / Mirowski, M.; Reid, P. R.; Mower, Morton Maimon; Watkins, L.; Gott, Vincent L; Schauble, J. F.; Langer, A.; Heilman, M. S.; Kolenik, S. A.; Fischell, R. E.; Weisfeldt, Myron.

In: New England Journal of Medicine, Vol. 303, No. 6, 1980, p. 322-324.

Research output: Contribution to journalArticle

Mirowski, M, Reid, PR, Mower, MM, Watkins, L, Gott, VL, Schauble, JF, Langer, A, Heilman, MS, Kolenik, SA, Fischell, RE & Weisfeldt, M 1980, 'Termination of malignant ventricular arrhythmias with an implanted automatic defibrillator in human beings', New England Journal of Medicine, vol. 303, no. 6, pp. 322-324.
Mirowski, M. ; Reid, P. R. ; Mower, Morton Maimon ; Watkins, L. ; Gott, Vincent L ; Schauble, J. F. ; Langer, A. ; Heilman, M. S. ; Kolenik, S. A. ; Fischell, R. E. ; Weisfeldt, Myron. / Termination of malignant ventricular arrhythmias with an implanted automatic defibrillator in human beings. In: New England Journal of Medicine. 1980 ; Vol. 303, No. 6. pp. 322-324.
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AU - Schauble, J. F.

AU - Langer, A.

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