Temporal repolarization lability differences among genotyped patients with the long QT syndrome

Kenneth Bilchick, Matti Viitasalo, Lasse Oikarinen, Barry Fetics, Gordon Tomaselli, Heikki Swan, Päivi J. Laitinen, Heikki Väänänen, Kimmo Kontula, Ronald D. Berger

Research output: Contribution to journalArticlepeer-review

Abstract

The investigators sought to test whether certain long QT syndrome (LQTS) mutations are associated with increased repolarization lability and whether repolarization lability (quantified by the QT variability index [QTVI]) is increased in patients with LQTS compared with controls. In 32 genotyped patients with LQTS type 1 (LQT1), 32 genotyped patients with LQTS type 2 (LQT2), and 32 controls, the QTVI was increased in patients with LQT2 (-0.973 ± 0.394, p = 0.01 vs controls) and in patients with LQT1 with mutations other than KCNQ1-FIN (-0.942 ± 0.264, p = 0.04 vs controls) but was similar between the KCNQ1-FIN group and controls.

Original languageEnglish (US)
Pages (from-to)1312-1316
Number of pages5
JournalAmerican Journal of Cardiology
Volume94
Issue number10
DOIs
StatePublished - Nov 15 2004

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Temporal repolarization lability differences among genotyped patients with the long QT syndrome'. Together they form a unique fingerprint.

Cite this