Telomerase: A promising marker of biological immortality of germ, stem, and cancer cells. A review

A. K. Meeker, D. S. Coffey

Research output: Contribution to journalArticlepeer-review

Abstract

This review will describe the current state of knowledge of telomerase as it relates to human malignancies, focusing primarily on published measurements of this enzymes activity in benign and malignant neoplasms and their normal tissue counterparts. Key questions concerning the potential clinical utility of assaying for telomerase activity will be addressed and the implications of recent findings discussed.

Original languageEnglish (US)
Pages (from-to)1323-1331
Number of pages9
JournalBiochemistry (Moscow)
Volume62
Issue number11
StatePublished - Dec 1 1997

Keywords

  • Cancer
  • Oncogenesis
  • Telomerase

ASJC Scopus subject areas

  • Biochemistry

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