Technology insight: can neuroimaging provide insights into the role of ischemia in Baló's concentric sclerosis?

Ellen Mahar Mowry, John H. Woo, Beau M. Ances

Research output: Contribution to journalArticle

Abstract

Baló's concentric sclerosis (BCS) has long been considered to be a variant of multiple sclerosis. Although BCS was initially described over 100 years ago, relatively few antemortem cases have been identified, and the exact pathogenesis remains unknown. Inflammatory protective ischemic preconditioning has recently been suggested as a mechanism by which the typical concentric rings of the BCS lesion are formed. Advanced neuroimaging can provide important in vivo markers of disease progression that can assist in the diagnosis and management of patients with BCS. In this Review, we discuss evidence from longitudinal neuroimaging studies that supports the role of ischemic preconditioning in BCS.

Original languageEnglish (US)
Pages (from-to)341-348
Number of pages8
JournalNature Clinical Practice Neurology
Volume3
Issue number6
DOIs
StatePublished - Jun 2007
Externally publishedYes

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Sclerosis
Neuroimaging
Ischemia
Technology
Ischemic Preconditioning
Multiple Sclerosis
Longitudinal Studies
Disease Progression

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Technology insight : can neuroimaging provide insights into the role of ischemia in Baló's concentric sclerosis? / Mowry, Ellen Mahar; Woo, John H.; Ances, Beau M.

In: Nature Clinical Practice Neurology, Vol. 3, No. 6, 06.2007, p. 341-348.

Research output: Contribution to journalArticle

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