Tc1 transposon-like sequences are widely distributed in salmonids

John L. Goodier, William S. Davidson

Research output: Contribution to journalArticlepeer-review

Abstract

Transposon-like elements flanked by inverted repeats, although common in invertebrates, have only recently been found in vertebrates. The report the presence of Tc1 transposon-like sequences in salmon, trout and charr species and find that these elements belong to several families that do not follow phylogenetic lines. As many as 15,000 copies reside in the Atlantic salmon haploid genome. The complete DNA sequence of one of these transposon-like elements (SALT1) is 1535 base-pairs long, including 35 nucleotide-long terminal inverted repeats. It contains a degenerate open reading frame (ORF) of 1273 nucleotides whose inferred amino acid sequence shares sequence similarity with the ‘D, D35E’ family of transposases, particularly those from Caenorhabditis sp. and Drosophila sp. Southern blot analysis indicated that Tc1 transposon-like sequences are present in other lower vertebrates, including several fish species and amphibians, but the copy number can vary significantly in different lineages.

Original languageEnglish (US)
Pages (from-to)26-34
Number of pages9
JournalJournal of molecular biology
Volume241
Issue number1
DOIs
StatePublished - Aug 4 1994
Externally publishedYes

Keywords

  • Atlantic salmon
  • Inverted repeats
  • Nematode
  • Transposable elements

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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