Targeting cancer cells with dendrimers

Srinivasa Gopalan Sampathkumar; Kevin J. Yarema

doi:10.1016/j.chembiol.2004.12.007

Targeting cancer cells with dendrimers

Srinivasa Gopalan Sampathkumar, Kevin J. Yarema

Research output: Contribution to journal › Short survey › peer-review

55 Scopus citations

Abstract

Bifunctional PAMAM-based dendrimers that selectively target cancer cells are described in this issue of Chemistry & Biology [1]. The targeting moiety for folate receptor is complexed to an imaging or therapeutic agent by a DNA "zipper" - a versatile strategy to create libraries of novel drugs.

Original language	English (US)
Pages (from-to)	5-6
Number of pages	2
Journal	Chemistry and Biology
Volume	12
Issue number	1
DOIs	https://doi.org/10.1016/j.chembiol.2004.12.007
State	Published - Jan 2005
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmacology
Drug Discovery
Clinical Biochemistry

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10.1016/j.chembiol.2004.12.007

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title = "Targeting cancer cells with dendrimers",

abstract = "Bifunctional PAMAM-based dendrimers that selectively target cancer cells are described in this issue of Chemistry & Biology [1]. The targeting moiety for folate receptor is complexed to an imaging or therapeutic agent by a DNA {"}zipper{"} - a versatile strategy to create libraries of novel drugs.",

author = "Sampathkumar, {Srinivasa Gopalan} and Yarema, {Kevin J.}",

year = "2005",

month = jan,

doi = "10.1016/j.chembiol.2004.12.007",

language = "English (US)",

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journal = "Chemistry and Biology",

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AU - Sampathkumar, Srinivasa Gopalan

AU - Yarema, Kevin J.

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AB - Bifunctional PAMAM-based dendrimers that selectively target cancer cells are described in this issue of Chemistry & Biology [1]. The targeting moiety for folate receptor is complexed to an imaging or therapeutic agent by a DNA "zipper" - a versatile strategy to create libraries of novel drugs.

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U2 - 10.1016/j.chembiol.2004.12.007

DO - 10.1016/j.chembiol.2004.12.007

M3 - Short survey

C2 - 15664507

AN - SCOPUS:12344270140

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VL - 12

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JO - Chemistry and Biology

JF - Chemistry and Biology

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ER -

Targeting cancer cells with dendrimers

Abstract

ASJC Scopus subject areas

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