Targeting and retention of Golgi membrane proteins

Research output: Contribution to journalArticlepeer-review

91 Scopus citations


Recent cloning of genes encoding membrane proteins of the Golgi complex has allowed investigation of protein targeting to this organelle. Targeting signals have been identified in three glycosyltransferases, a viral envelope protein and several proteins of the trans-Golgi network. Interestingly, the targeting signals for membrane proteins of the Golgi stacks seem to be contained in transmembrane domains. Information in the cytoplasmic tails is required for the targeting of trans-Golgi network proteins. Mechanisms involving both retention and retrieval have been invoked.

Original languageEnglish (US)
Pages (from-to)606-612
Number of pages7
JournalCurrent Opinion in Cell Biology
Issue number4
StatePublished - Aug 1993

ASJC Scopus subject areas

  • Cell Biology


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