Targeted Prostate Biopsy Using 68Gallium PSMA-PET/CT for Image Guidance

Demetrios N. Simopoulos, Shyam Natarajan, Tonye A. Jones, Wolfgang P. Fendler, Anthony E. Sisk, Leonard S. Marks

Research output: Contribution to journalArticle

Abstract

Prostate specific membrane antigen (PSMA) scanning is a sensitive method of prostate cancer detection. In a 71 y.o. man with a PSA of 49 (6%F), 4 negative MRI studies and 6 negative biopsies over an 8 year interval, a 68Ga-PSMA PET/CT scan showed a PSMA-avid spot in the prostate. Using image fusion technology, the lesion was target-biopsied and Gleason 3 + 4 = 7 (cancer core length of 12 mm) was identified. This case may herald a new application for PSMA scanning and prostate cancer imaging.

Original languageEnglish (US)
Pages (from-to)11-14
Number of pages4
JournalUrology Case Reports
Volume14
DOIs
StatePublished - Sep 2017
Externally publishedYes

Keywords

  • PSMA
  • Prostate cancer
  • Targeted biopsy
  • mpMRI

ASJC Scopus subject areas

  • Urology

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