Targeted Prostate Biopsy Using 68Gallium PSMA-PET/CT for Image Guidance

Demetrios Simopoulos, Shyam Natarajan, Tonye A. Jones, Wolfgang P. Fendler, Anthony E. Sisk, Leonard S. Marks

Research output: Contribution to journalArticle

Abstract

Prostate specific membrane antigen (PSMA) scanning is a sensitive method of prostate cancer detection. In a 71 y.o. man with a PSA of 49 (6%F), 4 negative MRI studies and 6 negative biopsies over an 8 year interval, a 68Ga-PSMA PET/CT scan showed a PSMA-avid spot in the prostate. Using image fusion technology, the lesion was target-biopsied and Gleason 3 + 4 = 7 (cancer core length of 12 mm) was identified. This case may herald a new application for PSMA scanning and prostate cancer imaging.

Original languageEnglish (US)
Pages (from-to)11-14
Number of pages4
JournalUrology Case Reports
Volume14
DOIs
StatePublished - Sep 1 2017
Externally publishedYes

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Prostate
Biopsy
Prostatic Neoplasms
Technology
human glutamate carboxypeptidase II
Neoplasms

Keywords

  • mpMRI
  • Prostate cancer
  • PSMA
  • Targeted biopsy

ASJC Scopus subject areas

  • Urology

Cite this

Simopoulos, D., Natarajan, S., Jones, T. A., Fendler, W. P., Sisk, A. E., & Marks, L. S. (2017). Targeted Prostate Biopsy Using 68Gallium PSMA-PET/CT for Image Guidance. Urology Case Reports, 14, 11-14. https://doi.org/10.1016/j.eucr.2017.05.006

Targeted Prostate Biopsy Using 68Gallium PSMA-PET/CT for Image Guidance. / Simopoulos, Demetrios; Natarajan, Shyam; Jones, Tonye A.; Fendler, Wolfgang P.; Sisk, Anthony E.; Marks, Leonard S.

In: Urology Case Reports, Vol. 14, 01.09.2017, p. 11-14.

Research output: Contribution to journalArticle

Simopoulos, Demetrios ; Natarajan, Shyam ; Jones, Tonye A. ; Fendler, Wolfgang P. ; Sisk, Anthony E. ; Marks, Leonard S. / Targeted Prostate Biopsy Using 68Gallium PSMA-PET/CT for Image Guidance. In: Urology Case Reports. 2017 ; Vol. 14. pp. 11-14.
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