Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

L. Bi, A. M. Lawler, S. E. Antonarakis, K. A. High, J. D. Gearhart, H. H. Kazazian

Research output: Contribution to journalArticle

Abstract

Haemophilia A is a classic X-linked disease which affects 1 in 5-10,000 males in all populations and is caused by defects in coagulation factor VIII. Roughly 60% of patients have severe disease with factor VIII activity

Original languageEnglish (US)
Pages (from-to)119-121
Number of pages3
JournalNature Genetics
Volume10
Issue number1
StatePublished - 1995

Fingerprint

Factor VIII
Hemophilia A
Genes
Population

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this

Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A. / Bi, L.; Lawler, A. M.; Antonarakis, S. E.; High, K. A.; Gearhart, J. D.; Kazazian, H. H.

In: Nature Genetics, Vol. 10, No. 1, 1995, p. 119-121.

Research output: Contribution to journalArticle

Bi, L, Lawler, AM, Antonarakis, SE, High, KA, Gearhart, JD & Kazazian, HH 1995, 'Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A', Nature Genetics, vol. 10, no. 1, pp. 119-121.
Bi, L. ; Lawler, A. M. ; Antonarakis, S. E. ; High, K. A. ; Gearhart, J. D. ; Kazazian, H. H. / Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A. In: Nature Genetics. 1995 ; Vol. 10, No. 1. pp. 119-121.
@article{7fec9b6130b04e1fa235039be3c309aa,
title = "Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A",
abstract = "Haemophilia A is a classic X-linked disease which affects 1 in 5-10,000 males in all populations and is caused by defects in coagulation factor VIII. Roughly 60{\%} of patients have severe disease with factor VIII activity",
author = "L. Bi and Lawler, {A. M.} and Antonarakis, {S. E.} and High, {K. A.} and Gearhart, {J. D.} and Kazazian, {H. H.}",
year = "1995",
language = "English (US)",
volume = "10",
pages = "119--121",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "Nature Publishing Group",
number = "1",

}

TY - JOUR

T1 - Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

AU - Bi, L.

AU - Lawler, A. M.

AU - Antonarakis, S. E.

AU - High, K. A.

AU - Gearhart, J. D.

AU - Kazazian, H. H.

PY - 1995

Y1 - 1995

N2 - Haemophilia A is a classic X-linked disease which affects 1 in 5-10,000 males in all populations and is caused by defects in coagulation factor VIII. Roughly 60% of patients have severe disease with factor VIII activity

AB - Haemophilia A is a classic X-linked disease which affects 1 in 5-10,000 males in all populations and is caused by defects in coagulation factor VIII. Roughly 60% of patients have severe disease with factor VIII activity

UR - http://www.scopus.com/inward/record.url?scp=0029011723&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029011723&partnerID=8YFLogxK

M3 - Article

C2 - 7647782

AN - SCOPUS:0029011723

VL - 10

SP - 119

EP - 121

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 1

ER -