Cancer continues to be the major cause of morbidity and death of more than 500,000 people in the US annually. Alternatively activated macrophages (M2 macrophages or TAMs) can facilitate tumor invasiveness and metastasis. As an invasive species in the tumor microenvironment, they provide an ideal therapeutic target.
- Epithelial to mesenchymal transition
- Prostate cancer
- Tumor associated macrophages
ASJC Scopus subject areas
- Immunology and Allergy