Tall cell papillary thyroid cancer: Incidence and prognosis

James H. Terry, Susan A St John, Frederick J. Karkowski, Jorge R. Suarez, Naguib H. Yassa, Corneliu D. Platica, Jose R. Marti

Research output: Contribution to journalArticle

Abstract

Background: The tall cell variant (TCV) of papillary thyroid cancer is reported to have a poor prognosis. This study examines the incidence and end result of surgical treatment of TCV. Methods: In this study, 240 thyroid cancers treated over a 23-year period at two hospital centers are reviewed. A total of 153 patients with papillary cancer were available for follow-up. All microscopic slides were re-examined. Results: Of the total 183 papillary cancers, 19 (10.4%) were TCV. The remainder were usual papillary or other papillary cancer variants. Patient age, tumor size, lymph node and soft-tissue involvement, recurrence, and death rates were evaluated. Multivariate statistical analysis disclosed that TCV histology, as well as age and tumor size, were significant predictors of recurrence. conclusion: Despite a high rate of recurrence in TCV cases over age 50 (6/9), there were no recurrent TCVs in cases under age 50 (0/8). Pathologists and surgeons must develop an increased awareness of this entity and implications for more radical treatment in the older age group.

Original languageEnglish (US)
Pages (from-to)459-461
Number of pages3
JournalAmerican Journal of Surgery
Volume168
Issue number5
DOIs
StatePublished - 1994
Externally publishedYes

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Incidence
Neoplasms
Recurrence
Thyroid Neoplasms
Histology
Cohort Studies
Multivariate Analysis
Age Groups
Lymph Nodes
Papillary Thyroid cancer
Mortality
Therapeutics
Surgeons
Pathologists

ASJC Scopus subject areas

  • Surgery

Cite this

Terry, J. H., John, S. A. S., Karkowski, F. J., Suarez, J. R., Yassa, N. H., Platica, C. D., & Marti, J. R. (1994). Tall cell papillary thyroid cancer: Incidence and prognosis. American Journal of Surgery, 168(5), 459-461. https://doi.org/10.1016/S0002-9610(05)80099-6

Tall cell papillary thyroid cancer : Incidence and prognosis. / Terry, James H.; John, Susan A St; Karkowski, Frederick J.; Suarez, Jorge R.; Yassa, Naguib H.; Platica, Corneliu D.; Marti, Jose R.

In: American Journal of Surgery, Vol. 168, No. 5, 1994, p. 459-461.

Research output: Contribution to journalArticle

Terry, JH, John, SAS, Karkowski, FJ, Suarez, JR, Yassa, NH, Platica, CD & Marti, JR 1994, 'Tall cell papillary thyroid cancer: Incidence and prognosis', American Journal of Surgery, vol. 168, no. 5, pp. 459-461. https://doi.org/10.1016/S0002-9610(05)80099-6
Terry JH, John SAS, Karkowski FJ, Suarez JR, Yassa NH, Platica CD et al. Tall cell papillary thyroid cancer: Incidence and prognosis. American Journal of Surgery. 1994;168(5):459-461. https://doi.org/10.1016/S0002-9610(05)80099-6
Terry, James H. ; John, Susan A St ; Karkowski, Frederick J. ; Suarez, Jorge R. ; Yassa, Naguib H. ; Platica, Corneliu D. ; Marti, Jose R. / Tall cell papillary thyroid cancer : Incidence and prognosis. In: American Journal of Surgery. 1994 ; Vol. 168, No. 5. pp. 459-461.
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