TY - JOUR
T1 - Talc Retinopathy in Primates
T2 - A Model of Ischemic Retinopathy: III. An Electron Microscopic Study
AU - Kaga, Norio
AU - Tso, Mark O.M.
AU - Jampol, Lee M.
PY - 1982/10
Y1 - 1982/10
N2 - Electron microscopic study of experimental talc retinopathy provides an opportunity to study the basic cytologic response of retinal and choroidal vessels to small, relatively inert emboli. Occlusion of the retinal and choroidal capillaries resulted primarily from the cellular reaction to, rather than directly from, the emboli. Mitotic figures in pericytes were observed. Even though we failed to produce retinal neovascularization (as is sometimes seen in human talc retinopathy) in this experimental model, our observations suggest that proliferation of pericytes may be an initial step in the process of retinal neovascularization.
AB - Electron microscopic study of experimental talc retinopathy provides an opportunity to study the basic cytologic response of retinal and choroidal vessels to small, relatively inert emboli. Occlusion of the retinal and choroidal capillaries resulted primarily from the cellular reaction to, rather than directly from, the emboli. Mitotic figures in pericytes were observed. Even though we failed to produce retinal neovascularization (as is sometimes seen in human talc retinopathy) in this experimental model, our observations suggest that proliferation of pericytes may be an initial step in the process of retinal neovascularization.
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U2 - 10.1001/archopht.1982.01030040627015
DO - 10.1001/archopht.1982.01030040627015
M3 - Article
C2 - 7138334
AN - SCOPUS:0019955444
SN - 0003-9950
VL - 100
SP - 1649
EP - 1657
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 10
ER -